… Mitochondrial dysfunction is important in these pathological … role for mitochondria in the
coordination of pro-inflammatory … In this regard, mitochondrial reactive oxygen species are …

… generation of reactive oxygen species (ROS) … inflammation (1). Innate immune cells such
as macrophages and neutrophils produce and employ mitochondrial reactive oxygen species (…

… mitochondria generate and regulate the production of mtROS and the function of mtROS both
in physiological and pathological … inflammatory diseases and inflammatory malignancies. …

… and reactive oxygen species (ROS) as the most accepted cause of aging and numerous
inflammatory … states inhibits mitophagy (the removal of malfunctioning mitochondria through …

… has implicated mitochondrial reactive oxygen species (mtROS) in … mitochondria-targeted
inhibition of the oxidative stress in vivo to alleviate the clinical symptoms and lung inflammation …

… in several cell types (NOS2) in response to pro-inflammatory stimuli and produces large …
The physiological and pathological role of these reactive species in cellular activities will be …

… Mitochondrial reactive oxygen species (mROS) are routinely produced at several sites … play
a direct role in inflammation. Indeed, damaged mitochondria are held responsible for NLRP3 …

… and pathological endothelial cell activation and inflammation initiation; 4) Mitochondrial Ca
2+ … Continuous improvement of our understanding in this aspect of mitochondrial function …

Mitochondrial reactive oxygen species generation has been … inflammation are elusive. Herein
we explore the spatial–temporal relationship of oxidative/nitrative stress and inflammatory …

… Chronic inflammation is always pathological and a dysregulated inflammation results in …
pathway which is susceptible to changes in mitochondrial and intracellular ROS, as well as …