Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies

A Rimessi, M Previati, F Nigro, MR Wieckowski… - The international journal …, 2016 - Elsevier
… In this regard, mitochondrial reactive oxygen species are emerging as perfect liaisons that
mitochondrial mechanisms, including reactive oxygen species production and mitochondrial

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

X Li, P Fang, J Mai, ET Choi, H Wang… - Journal of hematology & …, 2013 - Springer
… A recent progress in characterizing mtROS has led to the generation of a new paradigm,
in which blockade of mtROS production may serve as a promising therapy for inhibiting …

Induction of reactive oxygen species: an emerging approach for cancer therapy

Z Zou, H Chang, H Li, S Wang - Apoptosis, 2017 - Springer
treatments with ROS-induced agents will be considered as a promising strategy in cancer
therapy. In … Mitochondria-derived H 2 O 2 by sanguinarine treatment induces autophagic cell …

Unraveling mitochondria‐targeting reactive oxygen species modulation and their implementations in cancer therapy by nanomaterials

H Peng, F Yao, J Zhao, W Zhang, L Chen, X Wang… - …, 2023 - Wiley Online Library
… Generally, their study combines the SDT and EMI methods for providing mitochondria-targeting
anticancer therapy as a promising strategy. Furthermore, this integration of EMI strategy …

Mitochondrial reactive oxygen species and cancer

LB Sullivan, NS Chandel - Cancer & metabolism, 2014 - Springer
… In addition, treatment of mitochondria-replete cells with the … to maintain homeostasis, a
promising therapeutic approach is to … In all cases, treatment with the identified small molecules …

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants

J Teixeira, CM Deus, F Borges, PJ Oliveira - The international journal of …, 2018 - Elsevier
… approaches have resulted in an approved drug for a mitochondrial therapy so far. … to improve
mitochondrial (dys)function has been growing in the last years. One viable and promising

Nanomedicines for reactive oxygen species mediated approach: an emerging paradigm for cancer treatment

S Kwon, H Ko, DG You, K Kataoka… - Accounts of Chemical …, 2019 - ACS Publications
… The integration of nanomedicine and ROS-mediated therapy has emerged as the new
paradigm in the treatment of cancer, based on promising proof-of-concept demonstrations in …

Mitochondrial complex II and reactive oxygen species in disease and therapy

K Hadrava Vanova, M Kraus, J Neuzil, J Rohlena - Redox Report, 2020 - Taylor & Francis
… -010 as possible candidates for cancer therapy [Citation110]. In … CII has potential in
combinational cancer therapy. This is in line … seems to be a promising tool for the treatment of …

[HTML][HTML] … of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

B Kalyanaraman, G Cheng, M Hardy, O Ouari… - Redox biology, 2018 - Elsevier
Reactive oxygen species (ROS) have been implicated in … of ROS generation, the mitochondria
and the NADPH oxidase … the methodologies to detect mitochondria-derived superoxide …

Small molecules regulating reactive oxygen species homeostasis for cancer therapy

J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
… be a promising treatment for … mitochondrial ROS production in cancer treatment may be
beneficial or harmful. However, the benefits of employing ROS-specific cancer targeted therapies