Mitochondrial dysfunction in atrial fibrillation—Mechanisms and pharmacological interventions
P Muszyński, TA Bonda - Journal of Clinical Medicine, 2021 - mdpi.com
… mitochondrial welfare. This review summarizes the mechanisms of mitochondrial dysfunction
related to atrial fibrillation … targeting mitochondria to prevent or improve the outcome of atrial …
related to atrial fibrillation … targeting mitochondria to prevent or improve the outcome of atrial …
Cellular and mitochondrial mechanisms of atrial fibrillation
… the path towards new therapeutic targets. In this review, we discuss the importance of
mitochondrial Ca 2+ handling in regulating ATP production and mitochondrial ROS emission and …
mitochondrial Ca 2+ handling in regulating ATP production and mitochondrial ROS emission and …
Mitochondria and the pathophysiological mechanism of atrial fibrillation
X Li, X Yang, Y Li, M Yuan, C Tian… - Current …, 2018 - ingentaconnect.com
… in mitochondrial distribution further imply that mitochondria … between mitochondria and AF,
and provide potential therapeutic … or indirect factors that affect mitochondria function and thus …
and provide potential therapeutic … or indirect factors that affect mitochondria function and thus …
The role of mitochondrial dysfunction in atrial fibrillation: translation to druggable target and biomarker discovery
L Pool, LFJM Wijdeveld, NMS de Groot… - International journal of …, 2021 - mdpi.com
… mitochondria dysfunction in AF is presented. We highlight the key modulators of mitochondrial
… they represent potential targets for therapeutic interventions and diagnostics in clinical AF. …
… they represent potential targets for therapeutic interventions and diagnostics in clinical AF. …
Mitochondrial oxidative stress promotes atrial fibrillation
… the role of mitochondrial ROS in atrial RyR2 … mitochondria to decrease mitochondrial ROS
production. RyR2-S2808D +/+ /mCAT mice exhibited significantly reduced atrial mitochondrial …
production. RyR2-S2808D +/+ /mCAT mice exhibited significantly reduced atrial mitochondrial …
Developing Pharmacological Therapies for Atrial Fibrillation Targeting Mitochondrial Dysfunction and Oxidative Stress: A Scoping Review
AS Menezes Júnior, ALG França-e-Silva… - International Journal of …, 2023 - mdpi.com
… the role of mitochondrial oxidative mechanisms in AF pathophysiology, the impact of
mitochondrial oxidative stress on AF initiation and perpetuation, and current therapies. This review …
mitochondrial oxidative stress on AF initiation and perpetuation, and current therapies. This review …
Sodium-glucose co-transporter 2 inhibition as a mitochondrial therapy for atrial fibrillation in patients with diabetes?
… atrial remodelling is a hallmark of AF and the degree of atrial … In summary, mitochondrial
dysfunction in atria from diabetic … targeting mitochondria could represent a feasible therapeutic …
dysfunction in atria from diabetic … targeting mitochondria could represent a feasible therapeutic …
Mitochondrial dysfunction underlies cardiomyocyte remodeling in experimental and clinical atrial fibrillation
M Wiersma, DMS van Marion, RCI Wüst… - Cells, 2019 - mdpi.com
… role of mitochondrial function in AF by measuring mitochondrial calcium … -1 atrial
cardiomyocytes induces mitochondrial Ca 2+ -handling changes, resulting in reduction in …
cardiomyocytes induces mitochondrial Ca 2+ -handling changes, resulting in reduction in …
Mitochondrial dysfunction in atrial tissue of patients developing postoperative atrial fibrillation
J Jeganathan, R Saraf, F Mahmood, A Pal… - The Annals of thoracic …, 2017 - Elsevier
… therapeutic intervention. … mitochondrial dysfunction by altering metabolic pathways, thus
leading to apoptosis and cell death. To establish this relationship, we studied the mitochondrial …
leading to apoptosis and cell death. To establish this relationship, we studied the mitochondrial …
Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation
KH Slagsvold, AB Johnsen, Ø Rognmo… - Physiological …, 2014 - journals.physiology.org
… Atrial fibrillation (AF) is the most common cardiac arrhythmia with a potential to cause serious
complications. Mitochondria … both mitochondrial function and the development of AF. Yet …
complications. Mitochondria … both mitochondrial function and the development of AF. Yet …
相关搜索
- atrial fibrillation mitochondrial dysfunction
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- postoperative atrial fibrillation
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- atrial fibrillation microrna expression profiles
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- atrial fibrillation cardiomyocyte remodeling
- atrial fibrillation heart failure
- atrial fibrillation mitral stenosis
- atrial fibrillation targeted therapy
- atrial fibrillation assessment of mitochondrial function
- atrial fibrillation risk in patients
- atrial fibrillation in diabetic rats
- patients with non-valvular paroxysmal atrial fibrillation
- mechanisms of atrial fibrillation
- atrial fibrillation in mice