When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death

FJ Bock, JS Riley - Cell Death & Differentiation, 2023 - nature.com
… In this review we discuss how the death receptor and mitochondrial pathways of apoptosis
… how cell death due to mitotic stress might be a special case when it comes to cell death and …

Mitotic cell death by chromosome fragmentation

JB Stevens, G Liu, SW Bremer, KJ Ye, W Xu, J Xu… - Cancer research, 2007 - AACR
… Here, we describe a new type of mitotic cell death, termed chromosome fragmentation,
which is a consequence of certain cellular stressors such as inherited genomic instability or …

Cell death by mitotic catastrophe: a molecular definition

M Castedo, JL Perfettini, T Roumier, K Andreau… - Oncogene, 2004 - nature.com
… to define mitotic catastrophe in morphological terms, namely, as a type of cell death
resulting from abnormal mitosis, which usually ends in the formation of large cells with multiple …

The cytoplasmic DNA sensor cGAS promotes mitotic cell death

C Zierhut, N Yamaguchi, M Paredes, JD Luo, T Carroll… - Cell, 2019 - cell.com
… of exposing cGAS to chromosomes upon mitotic nuclear envelope breakdown are unknown…
not effectively activated during normal mitosis. However, during mitotic arrest, low level cGAS…

Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

J H. HENDRY and CML WEST - International journal of radiation …, 1997 - Taylor & Francis
… Apoptosis is a process cell death results from `mitotic cell death’ and eg in the case of of
active cell death in the absence of immune surveilp53, any remaining p53-independent …

Mitotic death: a mechanism of survival? A review

J Erenpreisa, MS Cragg - Cancer cell international, 2001 - Springer
… of mitotic death do not simply represent aberrations of dying cells but are indicative of a
switch to amitotic modes of cell … In lymphoid and myeloid cell lines, all three types of cell death

hNuf2 inhibition blocks stable kinetochore–microtubule attachment and induces mitotic cell death in HeLa cells

JG DeLuca, B Moree, JM Hickey, JV Kilmartin… - The Journal of cell …, 2002 - rupress.org
… To further examine the pathway of mitotic exit by cell death resulting from depletion of
hNuf2, we determined the DNA content by flow cytometry (Fig. 2 E). 48 h after hNuf2 siRNA …

Mechanisms of Mitotic Cell Death Induced by Chemotherapy-Mediated G2 Checkpoint Abrogation

C Vogel, C Hager, H Bastians - Cancer Research, 2007 - AACR
mitotic cellscell death by inducing mitotic cell death or mitotic catastrophe (Supplementary
Fig. S2, refs. 16, 19, 20, 30). We asked whether this form of cell death represents a mitotic

Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death

BAA Weaver, DW Cleveland - Cancer cell, 2005 - cell.com
… that arrest, and cell death. In light of this evidence, we review here what is currently known
about the mitotic checkpoint and its role in tumorigenesis and cell death, and highlight some …

Death through a tragedy: mitotic catastrophe

H Vakifahmetoglu, M Olsson… - Cell Death & Differentiation, 2008 - nature.com
… drugs and mitotic failure caused by defective cell cycle checkpoints. … death-associated
MC is not a separate mode of cell death, rather a process (‘prestage’) preceding cell death