… in mixed solvents are able to reproduce protein–ligand … that a solvent site and a protein–ligand
interaction coincide whenever the distance between the solvent site center and the ligand …

… in mixed solvents.39·40 Nemethy and Scheraga3·37 calculated for an interaction between
leucine and phenylalanine a value of about 2 M-1 for $$ ) (25 C) in aqueous solution. …

… solvent acts as one of the ligands. Thermodynamic analysis then shows that thermodynamic
binding (ie, selective interaction… relative interaction of a solute and the principal solvent with …

… and formation of the corresponding mixed-ligand chelates. Organic solvents may be equally
well … is observed when nucleophilic species regarding the interactions with solvents and the …

… may be solvent-dependent: in water, an intramolecular stack is formed, while in the mixed
solvents, in … is solely dueto an intramolecular ligand-ligand interaction, a problem to be further …

… The influence of the solvent composition … solventdependent: in water, a “simple” (though
not rigid) intramolecular hydrophobic ligand-ligand adduct is formed, while in the mixed solvents…

… solvent molecules as detection probes. Exchange of magnetization between the "H nuclei of
the protein and the ligands through dipole-dipole interactions … and 100 ms mixing time. The …

… of the coordinated solvent form the equatorial … solvent molecules and phenoxy oxygen
atoms. Moreover, the self-assembly along the c axis with C–H⋯O and C–H⋯ π ring interactions …

… Ligands R(CH 2 ) n COO − with n = 0 or n > 1 form ternary complexes with a less pronounced
intramolecular stacking interaction. Variation of the solvent composition also leads to a …

… mixed solvents. For different compositions of organic … -ion interactions resulting from the
decreasing dielectric constant and from changes in solvent-ion and solvent-solvent interactions […