… The most potent anticancer agents in the current work 9g and 9k were chosen for the
assessment of apoptosis in MDA-MB-231cell line using Annexin V/propidium iodide (PI) double …

… To verify potential binding to anticancer drug targets, the interactions … modeling. Docking
and binding affinity calculations were carried out, in comparison with known anticancer agents …

… an anticancer agent. Molecular docking and dynamics simulations provided valuable insights
… Molecular docking and dynamics simulations provided valuable insights into the binding …

… In this section, we use the Hahnfeldt - Folkman model to give insights on this topic, and …
We illustrated through numerical simulations how our models could be used to give insights …

… of the derivatives showed unique insights, and all of the … The present study offers valuable
insights and a good starting … development of these useful potential anticancer agents. …

… provide invaluable additional insights into the models of cancer progression and treatment.
In theory, these concepts can address the fundamental challenges of anticancer therapy by …

… I HDAC inhibitors may lead to more effective anticancer agents than the pan-HDAC inhibitors
… models bearing either solid tumors or hematologic malignancies. The solid tumor models …

Human health is experiencing several obstacles in the modern medical era, particularly
cancer. As a result, the cancer therapeutic arsenal should be continually expanded with …

Unfolded protein response (UPR)-dependent metabolic reprogramming diverts metabolites
from glycolysis to mitochondrial 1C metabolism, highlighting pharmacological resistance to …

Small-molecule kinase inhibitors are being continuously explored as new anticancer therapeutics.
Kinases are the phosphorylating enzymes which regulate numerous cellular functions …