… and image analysis techniques to further our understanding of how cell signaling correlates
in time and space with protrusion of the cell's leading edge. Machacek et al. developed an …

… Some of the pathways initiallydiverging from this common source (through A, B, and D in…
signaling pathways are highly interconnected andthat a single stimulus can affect multiple cell …

… pathways. This type of framework has been suggested recently for modeling cell-signaling
pathways … as to whether this bacterial chemotaxis signaling pathway is essentially singular in …

… Although no one CSC model will be sufficient to explain how all cancers develop, or even to
… to many of these hypothetical models is the dysregulation of key signaling pathways. Further …

… The modeling of cellular signaling pathways is an emerging field. Sachs et al. illustrate …
cellular pathway involving the activation of focal adhesion kinase (FAK) and extracellular signal-…

… mechanisms, the interaction of various signaling pathways, the long-term effects of Ca 2+
-mobilizing agonists, and the mechanism terminating Ca 2+ signaling. Finally, we summarize …

… fitting of mathematical models of cell signaling pathways. Such models frequently take
the form of a set of nonlinear ordinary differential equations. While the model is continuous-time, …

… to modeling interactions in cell and cell population on the … to modeling of the dynamics of cell
signaling pathways takes … a deterministic description of cell signaling pathways [14], [17], [25…

… we will illustrate the modeling of signaling pathways with examples from different cell types
and discuss some problems that we consider open in the modeling of such pathways. We will …

… [2] In this study we restrict ourselves to a subset of modeling studies that deal with signaling
pathways. Protein structure, genetic interactions, and statistical analysis of large biological …