Modification of mesenchymal stem cells for cardiac regeneration
Importance of the field: Mesenchymal stem cells (MSCs) have the greatest potential for use
in cell-based therapy of human heart diseases, especially in myocardial infarcts. The …
in cell-based therapy of human heart diseases, especially in myocardial infarcts. The …
[HTML][HTML] Improved therapeutics of modified mesenchymal stem cells: an update
DKW Ocansey, B Pei, Y Yan, H Qian, X Zhang… - Journal of translational …, 2020 - Springer
… modification approaches can be broadly divided into two groups to include genetic modification
and preconditioning modification (… We discuss the application of the improved modified …
and preconditioning modification (… We discuss the application of the improved modified …
[HTML][HTML] Modification of mesenchymal stem cells for cartilage-targeted therapy
… homing capacity of MSCs and targeted modification can improve their ability to promote …
effect of stem cells in joints and highlight progress toward the targeted modification of MSCs. In …
effect of stem cells in joints and highlight progress toward the targeted modification of MSCs. In …
Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia
K Toyama, O Honmou, K Harada, J Suzuki… - Experimental …, 2009 - Elsevier
… transplantation of human mesenchymal stem cells (hMSCs) … effects of angiopoietin-1
gene-modified hMSC (Ang-hMSC), … of Ang-1 and VEGF gene-modified hMSCs (Ang-VEGF-hMSC) …
gene-modified hMSC (Ang-hMSC), … of Ang-1 and VEGF gene-modified hMSCs (Ang-VEGF-hMSC) …
Interferon-gamma modification of mesenchymal stem cells: implications of autologous and allogeneic mesenchymal stem cell therapy in allotransplantation
KN Sivanathan, S Gronthos, D Rojas-Canales… - Stem Cell Reviews and …, 2014 - Springer
… mesenchymal stem cells (MSC) as immune regulatory cells represent a promising approach
to modulate T cell … Zealand as the world’s first stem cell drug from Osiris therapeutics for the …
to modulate T cell … Zealand as the world’s first stem cell drug from Osiris therapeutics for the …
Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium
J Huang, Z Zhang, J Guo, A Ni, A Deb, L Zhang… - Circulation …, 2010 - Am Heart Assoc
… vivo salutary effects of genetic modification of stem cells. Specifically, overexpression of …
mesenchymal stem cells have been extensively investigated for their potential in developing cell …
mesenchymal stem cells have been extensively investigated for their potential in developing cell …
[HTML][HTML] Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia
… cell therapies has the potential to significantly enhance the therapeutic value of mesenchymal
stem cells (… of time, without adversely affecting cell viability and differentiation capacity, is …
stem cells (… of time, without adversely affecting cell viability and differentiation capacity, is …
Epitranscriptomic modifications in mesenchymal stem cell differentiation: advances, mechanistic insights, and beyond
J Zheng, Y Lu, Y Lin, S Si, B Guo, X Zhao… - Cell Death & …, 2024 - nature.com
… of different RNA modifications in MSCs, their roles in regulating stem cell behavior, and their
… modifications impact MSC biology, the functional significance of individual modifications, …
… modifications impact MSC biology, the functional significance of individual modifications, …
Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia
H Liu, O Honmou, K Harada, K Nakamura, K Houkin… - Brain, 2006 - academic.oup.com
Intravenous delivery of mesenchymal stem cells (MSCs) prepared from adult bone marrow
reduces infarction size and ameliorates functional deficits in rat cerebral ischaemia models. …
reduces infarction size and ameliorates functional deficits in rat cerebral ischaemia models. …
[HTML][HTML] A revealing review of mesenchymal stem cells therapy, clinical perspectives and Modification strategies
P Saeedi, R Halabian, AAI Fooladi - Stem cell investigation, 2019 - ncbi.nlm.nih.gov
… Multipotent mesenchymal stem cells (MSCs) have been considerably inspected as effective
tool for cell-based therapy of inflammatory, immune-mediated, and degenerative diseases, …
tool for cell-based therapy of inflammatory, immune-mediated, and degenerative diseases, …
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