Peripheral galanin receptor 2 as a target for the modulation of pain
RP Hulse, LF Donaldson… - Pain research and …, 2012 - Wiley Online Library
… with particular reference to the dual actions of the galanin receptor 2 in neuropathic pain …
of galanin receptors on primary afferent nociceptors as a possible target for pain treatment. …
of galanin receptors on primary afferent nociceptors as a possible target for pain treatment. …
Galanin plays a role in antinociception via binding to galanin receptors in the nucleus accumbens of rats with neuropathic pain
Y Zhang, Y Gao, CY Li, W Dong, MN Li, YN Liu… - Neuroscience …, 2019 - Elsevier
… Galanin and galanin receptors (GalRs) play important roles in the transmission and
modulation of nociceptive information. Our previous research has shown that the expression of …
modulation of nociceptive information. Our previous research has shown that the expression of …
Galanin and spinal pain mechanisms: past, present, and future
XJ Xu, T Hökfelt, Z Wiesenfeld-Hallin - Galanin, 2010 - Springer
… suggested physiological function for this peptide is pain modulation at the level of the spinal
… or neonatal capsaicin, indicating that galanin receptors mainly are present on postsynaptic …
… or neonatal capsaicin, indicating that galanin receptors mainly are present on postsynaptic …
[PDF][PDF] Galanin receptor 1 plays an antinociceptive effect via inhibiting PKA activation in the nucleus accumbens of rats with neuropathic pain
Y Zhang, Y Gao, CY Li, W Dong, Y Dong… - Physiological …, 2019 - biomed.cas.cz
… galanin and its receptors in antinociception in nucleus accumbens of rats with inflammatory
pain. … LC: Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior …
pain. … LC: Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior …
A new gal in town: a systematic review of the role of galanin and its receptors in experimental pain
D Fonseca-Rodrigues, A Almeida, F Pinto-Ribeiro - Cells, 2022 - mdpi.com
… that intrathecal administration of the putative galanin receptor antagonist M35 (galanin-(1–13)-…
the role of galanin in pain modulation in the brain. In the studies included in this review, …
the role of galanin in pain modulation in the brain. In the studies included in this review, …
Activation of peripheral galanin receptors: differential effects on nociception
JM Jimenez-Andrade, L Lundström… - Pharmacology …, 2006 - Elsevier
… While the role of GAL has been extensively studied in diverse pain models, the contribution
of each GalR subtype to pain modulation is not fully understood partially due to the lack of …
of each GalR subtype to pain modulation is not fully understood partially due to the lack of …
Involvement of galanin and galanin receptor 1 in nociceptive modulation in the central nucleus of amygdala in normal and neuropathic rats
SY Li, ML Huo, XY Wu, YQ Huang, L Wang, X Zhang… - Scientific Reports, 2017 - nature.com
… studies demonstrated that galanin receptors are involved in the pain modulation in the brain…
Kong and Yu have demonstrated that GalR1 is involved in the pain modulation in the brain …
Kong and Yu have demonstrated that GalR1 is involved in the pain modulation in the brain …
Galanin receptors possibly modulate the obesity-induced change in pain threshold
M Yu, P Fang, M Shi, Y Zhu, Y Sun, Q Li, P Bo, Z Zhang - Peptides, 2013 - Elsevier
… and between galanin and injure-induced pain. In view of the above, we reasoned that
galanin receptors possibly participated in the modulation of the obesity-induced change in pain …
galanin receptors possibly participated in the modulation of the obesity-induced change in pain …
Pro-nociceptive role of peripheral galanin in inflammatory pain
JM Jimenez-Andrade, S Zhou, J Du, A Yamani… - Pain, 2004 - Elsevier
… In summary, our findings suggest that peripheral GAL modulates VR1 function and has
an excitatory role under acute inflammatory conditions. This excitatory effect is likely to be …
an excitatory role under acute inflammatory conditions. This excitatory effect is likely to be …
Mechanism by which peripheral galanin increases acute inflammatory pain
JM Jimenez-Andrade, S Zhou, A Yamani, SV De Ita… - Brain research, 2005 - Elsevier
Galanin (GAL) is a neuropeptide involved in pain transmission. Intraplantar GAL at low doses
enhances capsaicin (CAP)-induced pain behaviors in rat, suggesting an excitatory role for …
enhances capsaicin (CAP)-induced pain behaviors in rat, suggesting an excitatory role for …
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