Immunomodulatory effects of stem cells

N Wada, S Gronthos, PM Bartold - Periodontology 2000, 2013 - Wiley Online Library
… A number of reports have shown that the potent anti-inflammatory and immune-modulating
properties of mesenchymal stem cells are largely associated with the inhibition of T-…

Mesenchymal stem cell‐derived factors: Immuno‐modulatory effects and therapeutic potential

V Volarevic, M Gazdic, B Simovic Markovic… - Biofactors, 2017 - Wiley Online Library
… HLA-G is a non-classical MHC class I molecule with immuno-modulatory properties, which
has been identified in both membrane bound and soluble forms 98. MSC-derived HLA-G is …

Comparative study of immune regulatory properties of stem cells derived from different tissues

M Di Trapani, G Bassi, M Ricciardi… - Stem cells and …, 2013 - liebertpub.com
… In other words, our data suggest that the immune modulatory properties of CSCs and LSCs
here described in vitro for the first time may have a role in vivo in favoring their regenerative …

Treatment of collagen-induced arthritis using immune modulatory properties of human mesenchymal stem cells

KH Park, CH Mun, MI Kang, SW Lee… - Cell …, 2016 - journals.sagepub.com
… Mesenchymal stem cells (MSCs) have immune modulatory properties. We investigated
the potential therapeutic effects of human bone marrow (BM)-, adipose tissue (AD)-, and cord …

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

CJ Chang, CH Chao, W Xia, JY Yang, Y Xiong… - Nature cell …, 2011 - nature.com
… in normal stem cell and neoplastic stem cell population as it … stemness properties 3,4 . All
these results suggest that miR-200c may have an integral role in modulating EMT and stem cell

Mesenchymal stem cell‐based immunomodulation: properties and clinical application

M Wang, Q Yuan, L Xie - Stem cells international, 2018 - Wiley Online Library
… MSCs are multipotent progenitor cells with multilineage differentiation potential and
immune-modulatory properties. MSCs have the ability to interact with immune cells both in innate …

Modulatory properties of extracellular matrix glycosaminoglycans and proteoglycans on neural stem cells behavior: Highlights on regenerative potential and bioactivity

Z Shabani, T Ghadiri, M Karimipour… - International Journal of …, 2021 - Elsevier
… and safe stem cell therapy in regenerative medicine approaches [2]. Therefore, addressing
the stem cells fate regulators and their mechanisms of action can improve stem cell-based …

Metabolic determinants of the immune modulatory function of neural stem cells

D Drago, V Basso, E Gaude, G Volpe… - Journal of …, 2016 - Springer
… To understand whether changes in arginase activity in NSCs could be involved in their
immune modulatory properties, we treated NSCs with the pan-arginase inhibitor nor-NOHA. We …

miR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2

C Xu, G Ren, G Cao, Q Chen, P Shou, C Zheng… - Journal of Biological …, 2013 - ASBMB
… role of miR-155 in regulating the immune modulatory activities of MSCs. … property of MSCs
is not innate but rather induced by inflammatory cytokines produced by inflammatory cells. In …

SOCS1 regulates the immune modulatory properties of mesenchymal stem cells by inhibiting nitric oxide production

L Zhang, RJ Dang, H Li, P Li, YM Yang, XM Guo… - PLoS …, 2014 - journals.plos.org
Mesenchymal stem cells (MSCs) have been shown to be highly … the proliferation and
differentiation properties of MSCs. However… in regulating the immune modulatory activities of …