… of the molecular mechanisms involved in abnormal lactotrope cell … of aggressive
prolactinomas. Indeed, Prlr knockout mice may constitute a good model of aggressive prolactinomas …

… Aggressive prolactinoma (APRL) is a subgroup of aggressive pituitary tumors (accounting
for 10% of all hypophyseal neoplasia) which are defined by: invasion based on radiological …

… In case 2, while the high number of mitoses with abnormalities … Fragments of tumors of both
cases were frozen for molecular … of prolactinomas [3]. Imaging suggested giant or invasive …

… within the incidence of aggression and invasion among the … Because the aggressive
behavior of invasive adenomas is … In fact, the invasive tumors with local extreme aggression are …

… cured by treatment, and that of aggressive tumours, and carcinomas with metastasis. …
molecular factors is essential for the early identification of patients that may have such aggressive …

… , including structural chromosomal abnormalities, genetic … who harbored multiple molecular
abnormalities. Despite multiple … a review of molecular abnormalities and management of …

… to be relatively specific markers for prolactinoma invasiveness compared with other pituitary
… to clarify the molecular mechanisms behind the aggressive course of some prolactinomas to …

… Despite many genetic abnormalities being described, the molecular pathophysiology of
prolactinomas, particularly those with an aggressive clinical course, remains largely obscure. …

… Hence, clinical, pathological, and molecular definitions of aggressive prolactinomas …
molecular endocrinological features of dopamine agonist-resistant and aggressive prolactinomas …

… effect including headaches and visual disturbances, and sexual … a rare and more
clinically aggressive subtype of lactotroph … Small fibrous bodies may be identified by low-molecular …