Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome

AR Hauser, DL Stevens, EL Kaplan… - Journal of clinical …, 1991 - Am Soc Microbiol
… -associated isolates containedthe gene encoding pyrogenic exotoxin type B. This … pyrogenic
toxin type C was found in only 21% of isolates. We conclude that the pyrogenic exotoxin

Bacterial pyrogenic exotoxins as superantigens

M Kotb - Clinical microbiology reviews, 1995 - Am Soc Microbiol
… of these molecules but because they utilize the class II molecules as signaling receptors
through which they can induce the APC to express the costimulatory molecules required for T-…

Staphylococcal enterotoxins, toxic shock syndrome toxin and streptococcal pyrogenic exotoxins: a comparative study of their molecular biology

MJ Betley, DW Borst, LB Regassa - Biological significance of …, 1992 - karger.com
Overview This article reviews molecular biological and genetic aspects of the staphylococcal
enterotoxins, toxic shock syndrome (TSS) toxins, and streptococcal pyrogenic exotoxins […

Similar cytokine induction profiles of a novel streptococcal exotoxin, MF, and pyrogenic exotoxins A and B

A Norrby-Teglund, M Norgren, SE Holm… - Infection and …, 1994 - Am Soc Microbiol
analysis of our exotoxin preparation, and at that time the protein was referred to as SpeC. This
was based on a highly similar molecular … In the present study the induction of 14 cytokines …

Molecular analysis of the role of streptococcal pyrogenic exotoxin A (SPEA) in invasive soft‐tissue infection resulting from Streptococcus pyogenes

S Sriskandan, M Unnikrishnan, T Krausz… - Molecular …, 1999 - Wiley Online Library
Epidemiological studies strongly implicate the bacterial superantigen, streptococcal pyrogenic
exotoxin A (SPEA), in the pathogenesis of necrotizing soft‐tissue infection and toxic shock …

Immunological and biochemical characterization of streptococcal pyrogenic exotoxins I and J (SPE-I and SPE-J) from Streptococcus pyogenes

T Proft, VL Arcus, V Handley, EN Baker… - The Journal of …, 2001 - journals.aai.org
… streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors.
… . Molecular analysis of the role of streptococcal pyrogenic exotoxin A (SPEA) in invasive soft-…

Streptococcal Superantigen, Mitogenic Factor, and Pyrogenic Exotoxin B Expressed by Streptococcus pyogenes Structure and Function

JM Musser - Preparative biochemistry & biotechnology, 1997 - Taylor & Francis
… In addition to the molecules noted above, several S. … genic exotoxin A (SPE A), pyrogenic
exotoxin B (SPE B), pyrogenic … idea that a molecule termed streptococcal pyogenic exotoxin B (…

Molecular Genetics of Pyrogenic Exotoxin “Superantigens” of Group A Streptococci and Staphylococcus aureus

PK Lee, PM Schlievert - Superantigens, 1991 - Springer
… C2, C3, D, and E, and staphylococcal pyrogenic exotoxins serotypes A and B. These toxins
share … we examine the molecular biological and biochemical relatedness of pyrogenic toxins. …

… Temporal Distribution and Molecular Characterization of Two Highly Pathogenic Clones of Streptococcus pyogenes Expressing Allelic Variants of Pyrogenic Exotoxin …

JM Musser, V Kapur, S Kanjilal, U Shah… - Journal of Infectious …, 1993 - academic.oup.com
Pyrogenic exotoxin production. The production of pyrogenic exotoxins was evaluated by
Ouchterlony immunodiffusion or Western immunoblot with hyperimmune rabbit antisera pre…

Analysis of the superantigenic activity of mutant and allelic forms of streptococcal pyrogenic exotoxin A

JB Kline, CM Collins - Infection and immunity, 1996 - Am Soc Microbiol
… and streptococcal pyrogenic exotoxins: a comparative study of their molecular biology. Chem.
Immunol. … Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates …