[HTML][HTML] Molecular approaches for spinal cord injury treatment
FM de Almeida, SA Marques… - Neural Regeneration …, 2023 - journals.lww.com
… on molecules that are being used, either in preclinical or clinical studies, to treat spinal cord
injuries, such … of action of these molecules are discussed, considering traumatic spinal cord …
injuries, such … of action of these molecules are discussed, considering traumatic spinal cord …
[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and targeted therapy, 2023 - nature.com
… Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the difficulties …
The challenges of SCI repair include its complex pathological mechanisms and the difficulties …
Cell and molecular approaches to the attenuation of pain after spinal cord injury
MJ Eaton - Journal of neurotrauma, 2006 - liebertpub.com
… Recent experimental research to treat spinal cord injury (SCI) pain has greatly increased
our understanding of how such chronic pain might be modulated in the human population. …
our understanding of how such chronic pain might be modulated in the human population. …
Advances in molecular therapies for targeting pathophysiology in spinal cord injury
HN Kim, MR McCrea, S Li - Expert opinion on therapeutic targets, 2023 - Taylor & Francis
… strategies, but many researchers employed other approaches to improve recovery after
SCI, including transplants of various types of cells or biomaterials, electrical and magnetic …
SCI, including transplants of various types of cells or biomaterials, electrical and magnetic …
[HTML][HTML] Pathophysiology and therapeutic approaches for spinal cord injury
… Molecular approaches focus on the modulation of a specific secondary event to promote
neuroprotection or neuroregeneration. The analysis of each drug considered the …
neuroprotection or neuroregeneration. The analysis of each drug considered the …
Molecular targets in spinal cord injury
S Klussmann, A Martin-Villalba - Journal of molecular medicine, 2005 - Springer
… It remains to be tested whether such an approach will also successfully ameliorate deficits
after SCI. In summary, several different approaches that aim at preventing inflammation …
after SCI. In summary, several different approaches that aim at preventing inflammation …
Emerging molecular therapeutic targets for spinal cord injury
… Here, we summarize the major advances in identifying therapeutic approaches to SCI in
mammalians, including neuroprotection, CNS regeneration, remyelination, and neuroplasticity, …
mammalians, including neuroprotection, CNS regeneration, remyelination, and neuroplasticity, …
[HTML][HTML] Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury
M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
… Current standard treatment modalities of the SCI … injury and provide limited recovery of lost
neurological functions. Stem Cell Therapy (SCT) represents an emerging treatment approach …
neurological functions. Stem Cell Therapy (SCT) represents an emerging treatment approach …
Miracles and molecules—progress in spinal cord repair
AR Blight - Nature neuroscience, 2002 - nature.com
… ways to improve the unsatisfactory cellular and molecular … recovery in a rat model of cord
injury 15 . There may be a number of practical hurdles to clinical development of this molecule, …
injury 15 . There may be a number of practical hurdles to clinical development of this molecule, …
Molecular approaches to spinal cord repair
… is on the potential use of antibodies, small molecules, peptides,neurotrophins, and enzymes
to neutralize axon growth inhibitors to foster axonregeneration after acute spinal cord injury. …
to neutralize axon growth inhibitors to foster axonregeneration after acute spinal cord injury. …
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