[HTML][HTML] Molecular approaches for spinal cord injury treatment

FM de Almeida, SA Marques… - Neural Regeneration …, 2023 - journals.lww.com
… on molecules that are being used, either in preclinical or clinical studies, to treat spinal cord
injuries, such … of action of these molecules are discussed, considering traumatic spinal cord

[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and targeted therapy, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the difficulties …

Cell and molecular approaches to the attenuation of pain after spinal cord injury

MJ Eaton - Journal of neurotrauma, 2006 - liebertpub.com
… Recent experimental research to treat spinal cord injury (SCI) pain has greatly increased
our understanding of how such chronic pain might be modulated in the human population. …

Advances in molecular therapies for targeting pathophysiology in spinal cord injury

HN Kim, MR McCrea, S Li - Expert opinion on therapeutic targets, 2023 - Taylor & Francis
… strategies, but many researchers employed other approaches to improve recovery after
SCI, including transplants of various types of cells or biomaterials, electrical and magnetic …

[HTML][HTML] Pathophysiology and therapeutic approaches for spinal cord injury

R Lima, A Monteiro, AJ Salgado, S Monteiro… - … Journal of Molecular …, 2022 - mdpi.com
Molecular approaches focus on the modulation of a specific secondary event to promote
neuroprotection or neuroregeneration. The analysis of each drug considered the …

Molecular targets in spinal cord injury

S Klussmann, A Martin-Villalba - Journal of molecular medicine, 2005 - Springer
… It remains to be tested whether such an approach will also successfully ameliorate deficits
after SCI. In summary, several different approaches that aim at preventing inflammation …

Emerging molecular therapeutic targets for spinal cord injury

S Wang, GM Smith, ME Selzer, S Li - Expert opinion on therapeutic …, 2019 - Taylor & Francis
… Here, we summarize the major advances in identifying therapeutic approaches to SCI in
mammalians, including neuroprotection, CNS regeneration, remyelination, and neuroplasticity, …

[HTML][HTML] Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury

M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
… Current standard treatment modalities of the SCI … injury and provide limited recovery of lost
neurological functions. Stem Cell Therapy (SCT) represents an emerging treatment approach

Miracles and molecules—progress in spinal cord repair

AR Blight - Nature neuroscience, 2002 - nature.com
ways to improve the unsatisfactory cellular and molecularrecovery in a rat model of cord
injury 15 . There may be a number of practical hurdles to clinical development of this molecule, …

Molecular approaches to spinal cord repair

S David, S Lacroix - Annual review of neuroscience, 2003 - annualreviews.org
… is on the potential use of antibodies, small molecules, peptides,neurotrophins, and enzymes
to neutralize axon growth inhibitors to foster axonregeneration after acute spinal cord injury. …