Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal domain suggests functional divergence among capsaicin receptor …
MA Schumacher, I Moff, SP Sudanagunta… - Journal of Biological …, 2000 - ASBMB
… capsaicin receptor. A cDNA was isolated that diverges with VR1 at its 5′ end and is termed
VR.5′sv. It is predicted to encode a capsaicin receptor … of receptors activated by capsaicin …
VR.5′sv. It is predicted to encode a capsaicin receptor … of receptors activated by capsaicin …
Molecular cloning, functional characterization of the porcine transient receptor potential V1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1
T Ohta, R Komatsu, T Imagawa, K Otsuguro… - Biochemical …, 2005 - Elsevier
… Recently, a functional capsaicin receptor termed vanilloid receptor 1 (VR1) has been cloned
… ion channels known as transient receptor potential (TRP) channels. Mice lacking the TRPV1 …
… ion channels known as transient receptor potential (TRP) channels. Mice lacking the TRPV1 …
Capsaicin receptor in the pain pathway
M Tominaga, D Julius - The Japanese Journal of Pharmacology, 2000 - jstage.jst.go.jp
… The cloned capsaicin receptor was designated vanilloid receptor … Other channels and
receptors clearly participate in the … Gene cloning and gene knockout studies will help to eluci…
receptors clearly participate in the … Gene cloning and gene knockout studies will help to eluci…
[PDF][PDF] The cloned capsaicin receptor integrates multiple pain-producing stimuli
M Tominaga, MJ Caterina, AB Malmberg, TA Rosen… - Neuron, 1998 - cell.com
… Under these conditions, we With the cloned capsaicin receptor … with capsaicin (Figure protons,
and vanilloid compounds on the … A recent review on the molecular biology of nociceptors …
and vanilloid compounds on the … A recent review on the molecular biology of nociceptors …
The capsaicin receptor: a heat-activated ion channel in the pain pathway
MJ Caterina, MA Schumacher, M Tominaga, TA Rosen… - Nature, 1997 - nature.com
… functional cDNA encoding a capsaicin receptor from sensory neurons. This receptor is a
non-… The cloned capsaicin receptor is also activated by increases in temperature in the noxious …
non-… The cloned capsaicin receptor is also activated by increases in temperature in the noxious …
Cloning and functional expression of a human orthologue of rat vanilloid receptor-1
P Hayes, HJ Meadows, MJ Gunthorpe, MH Harries… - Pain, 2000 - journals.lww.com
… a capsaicin sensitive phenotype. Here we describe the cloning of a human vanilloid receptor…
to the rat vanilloid receptor-1. Oocytes or mammalian cells expressing this cDNA respond to …
to the rat vanilloid receptor-1. Oocytes or mammalian cells expressing this cDNA respond to …
Capsaicin receptor immunoreactivity in the human trigeminal ganglion
M Hou, R Uddman, J Tajti, M Kanje, L Edvinsson - Neuroscience letters, 2002 - Elsevier
… -localizes with calcitonin gene-related peptide (CGRP), substance P (SP) and nitric oxide
synthase (NOS). This would support the hypothesis that the capsaicin receptor could modulate …
synthase (NOS). This would support the hypothesis that the capsaicin receptor could modulate …
Molecular cloning of a resiniferatoxin-binding protein
NN Ninkina, JJ Willoughby, MM Beech, PR Coote… - Molecular brain …, 1994 - Elsevier
… Evidence for a specific capsaicin receptor comes from structurefunction studies of capsaicin
… evidence that RBP-26 played a role in capsaicin receptor activity. Down-regulating the …
… evidence that RBP-26 played a role in capsaicin receptor activity. Down-regulating the …
Vanilloid (capsaicin) receptors in health and disease
A Szallasi - American journal of clinical pathology, 2002 - academic.oup.com
… Once a pharmacologic oddity, capsaicin has become a … molecular cloning of a complementary
DNA encoding a functional vanilloid (capsaicin) receptor, termed VR1 (vanilloid receptor …
DNA encoding a functional vanilloid (capsaicin) receptor, termed VR1 (vanilloid receptor …
A capsaicin-receptor homologue with a high threshold for noxious heat
MJ Caterina, TA Rosen, M Tominaga, AJ Brake… - Nature, 1999 - nature.com
… The cloned capsaicin receptor, also known as the vanilloid receptor subtype 1 (VR1), is a
heat-… Here we identify a structurally related receptor, VRL-1, that does not respond to capsaicin, …
heat-… Here we identify a structurally related receptor, VRL-1, that does not respond to capsaicin, …
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