Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer
JP Gillet, MM Gottesman - Current pharmaceutical …, 2011 - ingentaconnect.com
… levels of ABC transporters, by de… the molecular detection of ABC transporters and other
families of highly homologous MDR-linked genes encoding, for example, the uptake transporters (…
families of highly homologous MDR-linked genes encoding, for example, the uptake transporters (…
Molecular basis of multidrug transport by ABC transporters
MA Seeger, HW van Veen - Biochimica Et Biophysica Acta (BBA)-Proteins …, 2009 - Elsevier
… The expected asymmetry of a vanadate-trapped ABC transporter however was not detected
in a corresponding MsbA-ADP-V i crystal structure of MsbA, which was indistinguishable …
in a corresponding MsbA-ADP-V i crystal structure of MsbA, which was indistinguishable …
The role of ABC transporters in drug resistance, metabolism and toxicity
H Glavinas, P Krajcsi, J Cserepes… - Current drug …, 2004 - ingentaconnect.com
… We know very little as yet about the molecular mechanism and structure of these proteins, …
In this case radioactive labeling was utilized to detect molecules trapped inside the vesicles. …
In this case radioactive labeling was utilized to detect molecules trapped inside the vesicles. …
[HTML][HTML] Diverse relations between ABC transporters and lipids: An overview
J Neumann, D Rose-Sperling, UA Hellmich - Biochimica et Biophysica Acta …, 2017 - Elsevier
… also affect how ABC transporters interact with other hydrophobic molecules, such as …
molecules were detected for BtuCD using MS, but LDAO (lauryl dimethylamine N-oxide) molecules …
molecules were detected for BtuCD using MS, but LDAO (lauryl dimethylamine N-oxide) molecules …
[HTML][HTML] Molecular detection of lacrimal apparatus and ocular surface-related ABC transporter genes
B Kleinsasser, F Garreis, M Musialik, I Zahn… - Annals of Anatomy …, 2024 - Elsevier
… ABC transporters are expressed at the ocular surface and in the human lacrimal apparatus.
Using RT-PCR, all ABC transporters … the presence of all ABC transporters in the samples …
Using RT-PCR, all ABC transporters … the presence of all ABC transporters in the samples …
The role of ABC transporters in clinical practice
GD Leonard, T Fojo, SE Bates - The oncologist, 2003 - academic.oup.com
… Having outlined the difficulties in detecting MDR1/P-gp in cancer cells, it is not surprising that
… As molecular targets, ABC transporters may prove invaluable in facilitating the optimal use …
… As molecular targets, ABC transporters may prove invaluable in facilitating the optimal use …
Multidrug resistance in parasites: ABC transporters, P-glycoproteins and molecular modelling
PM Jones, AM George - International journal for parasitology, 2005 - Elsevier
… in these areas that the role of ABC transporters in parasitic multidrug resistance mechanisms
may … We discuss ABC transporters in parasites, and conclude with an example of molecular …
may … We discuss ABC transporters in parasites, and conclude with an example of molecular …
Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes
… As a strategy to explore which ABC transporters might function as drug transporters, we
performed COMPARE analysis with compounds included in the NCI’s Standard Agent database …
performed COMPARE analysis with compounds included in the NCI’s Standard Agent database …
ABC transporters affect the detection of intracellular oxidants by fluorescent probes
J Procházková, L Kubala, H Kotasová… - Free Radical …, 2011 - Taylor & Francis
… Second, we aimed to show that ROS detection could be affected by the endogenous expression
of ABC transporters. We showed that DCFH is a substrate of BCRP and, therefore, PMA-…
of ABC transporters. We showed that DCFH is a substrate of BCRP and, therefore, PMA-…
ABC drug transporters as molecular targets for the prevention of multidrug resistance and drug-drug interactions
AM Calcagno, IW Kim, CP Wu, S Shukla… - Current drug …, 2007 - ingentaconnect.com
… of ABC transporter expression would be helpful to detect any impending drug-drug interactions.
Many of the earliest detection systems for expression of ABC transporter genes utilized …
Many of the earliest detection systems for expression of ABC transporter genes utilized …
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