… In summary, the antitumor activity of the chalcone scaffolds is observed via distinct
mechanisms adopted by these molecules underlying their inhibitory activity (Scheme 5). …

… compound revealed that the chalcone scaffold is observed to … This binding orientation of
the chalcone scaffold is consistent … chalcone-coumarin hybrids as potential lead molecules for …

… Chalcone is the well exploited scaffold in the anticancer domain. The molecular mechanism
of chalcone … review provides the most recent updates on anticancer potential of chalcones. …

… This review provides an insight into the chemistry, … potential, chalcone scaffolds/chalcone
derivatives and … discovery toward promising drug lead molecules/drug candidates. …

… chalcone as a privileged scaffold, suitable for the development of antifungal agents. … some
liabilities of the chalcone scaffold and helped us to gain insight into the chemical features …

… Chalcones are a class of privileged scaffolds with high … Numerous functional modifications
of chalcones have been … -infectious diseases, and uses of chalcones over the past decade, …

… In order to evaluate the compounds pertaining to the chalcone scaffold, we used DataWarrior
Chemical Data Analysis and Visualization software V5.5.0 (López-López et al., Citation…

… chalcone scaffold were historically considered excellent candidates for the development of
anticancer drugs. Chalcones … promising therapeutic role of chalcones in TNBC management. …

… selectivity, the molecular modeling study was … insight on the inhibition mechanism and the
rational drug design of more potent/selective hMAO inhibitors based on the chalcone scaffold…

… To probe a deep insight into the binding interaction of chalcone with BSA, FT-IR spectra
were analyzed. Proteins exhibit two bands in the infrared region. The amide I band in the region …