[HTML][HTML] Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapy
… importance of molecular machineries related to the pH dysregulation within TME and that
the use of relevant inhibitors against key regulators of pH might suppress tumor progression, …
the use of relevant inhibitors against key regulators of pH might suppress tumor progression, …
Extracellular HSP90 machineries build tumor microenvironment and boost cancer progression
… Emerging data indicate that these functions are essential for tumor growth and progression.
… the molecular mechanisms at the basis of their functions in the tumor microenvironment may …
… the molecular mechanisms at the basis of their functions in the tumor microenvironment may …
[HTML][HTML] Dysregulated pH in tumor microenvironment checkmates cancer therapy
… Thus, the molecular machineries of this transitional step may provide potential target for
inhibition of type 3 EMT. In a study, the expressions of E-cadherin and ZO-1 were investigated in …
inhibition of type 3 EMT. In a study, the expressions of E-cadherin and ZO-1 were investigated in …
Impact of the physical microenvironment on tumor progression and metastasis
… tumor microenvironment and how its properties affect tumor … We will then introduce some
of the key intracellular molecules … cells that can activate mechanotransductive machinery and …
of the key intracellular molecules … cells that can activate mechanotransductive machinery and …
Turning cold into hot: firing up the tumor microenvironment
… Then, we discuss how innate immune sensing machinery, genetic alterations of oncogenic
… Those so-called hot tumors are characterized by T cell infiltration and molecular signatures …
… Those so-called hot tumors are characterized by T cell infiltration and molecular signatures …
Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?
F Chen, X Qi, M Qian, Y Dai, Y Sun - Protein & cell, 2014 - academic.oup.com
… -responsive molecular … machineries or the signals from extracellular environments are
actively at play under in vivo conditions. In contrast to other factors, the tumor microenvironment …
actively at play under in vivo conditions. In contrast to other factors, the tumor microenvironment …
Matrix metalloproteinases shape the tumor microenvironment in cancer progression
S Niland, AX Riscanevo, JA Eble - International journal of molecular …, 2021 - mdpi.com
… The tumor microenvironment (TME) is formed by cells as well as by biochemical and biophysical
components of the ECM and their intricate interactions in and around a solid tumor mass…
components of the ECM and their intricate interactions in and around a solid tumor mass…
Metabolic codependencies in the tumor microenvironment
P Dey, AC Kimmelman, RA DePinho - Cancer Discovery, 2021 - AACR
… into the regulation as well as the machinery involved in macropinocytosis and may provide
… In addition, signaling molecules from cancer cells can change the identity of immune cells …
… In addition, signaling molecules from cancer cells can change the identity of immune cells …
Roles of circRNAs in the tumour microenvironment
Q Zhang, W Wang, Q Zhou, C Chen, W Yuan, J Liu… - Molecular cancer, 2020 - Springer
… for cancer treatment, but their clinical applications are limited due to their toxic side effects [1].
The tumour microenvironment (TME… and therapeutic treatment of cancer [2,3,4]. Therefore, …
The tumour microenvironment (TME… and therapeutic treatment of cancer [2,3,4]. Therefore, …
Tumor microenvironment: the role of the tumor stroma in cancer
H Li, X Fan, JM Houghton - Journal of cellular biochemistry, 2007 - Wiley Online Library
… DNA mutations and the suppression of DNA repair machinery. The mutator phenotype of …
molecules unique to the tumor microenvironment will provide strategies for modifying the tumor …
molecules unique to the tumor microenvironment will provide strategies for modifying the tumor …
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