[HTML][HTML] Fates of CD8+ T cells in tumor microenvironment

NR Maimela, S Liu, Y Zhang - Computational and structural biotechnology …, 2019 - Elsevier
… the immunological responses of certain metastatic cancer patients [70,71]. CD27 and CD28
are costimulatory molecules of the tumor necosis receptor super family and immunoglobulin …

Molecular heterogeneity and immunosuppressive microenvironment in glioblastoma

S DeCordova, A Shastri, AG Tsolaki, H Yasmin… - Frontiers in …, 2020 - frontiersin.org
… Furthermore, this study also highlighted that the tumor microenvironment in recurrent GBM
showed the presence of more resident microglia/macrophages as compared to peripherally-…

Inhibitory B7-family molecules in the tumour microenvironment

W Zou, L Chen - Nature Reviews Immunology, 2008 - nature.com
… In this Review, we focus on the roles of these B7 molecules in the … in the tumour
microenvironment. We also discuss novel therapeutic strategies that target these inhibitory B7 …

Exosome-orchestrated hypoxic tumor microenvironment

W Meng, Y Hao, C He, L Li, G Zhu - Molecular cancer, 2019 - Springer
cancer cells and stroma are believed to regulate hypoxia-adaptation and to rebuild the
microenvironment in … among the variety of cell types within hypoxic cancer microenvironment. …

Toward understanding cancer stem cell heterogeneity in the tumor microenvironment

F Bocci, L Gearhart-Serna, M Boareto… - Proceedings of the …, 2019 - National Acad Sciences
… cues diffusing in the TME, noncell autonomous signaling via Notch-Jagged, and the
intracellular molecular machinery regulating EMT and CSC, however, remain largely elusive. …

Targeting tumor microenvironment in ovarian cancer: Premise and promise

Y Jiang, C Wang, S Zhou - … et Biophysica Acta (BBA)-Reviews on Cancer, 2020 - Elsevier
… Therefore, the molecular spectra of this aggressive tumor landscape warrants global efforts
Tumor microenvironment (TME) refers to the niche, either primary or metastatic, where tumor

The tumor microenvironment as a determinant of cancer cell survival: a possible mechanism for de novo drug resistance

KH Shain, TH Landowski… - Current opinion in …, 2000 - journals.lww.com
… of the tumor with extracellular matrix molecules; and interaction of the tumor with adjacent
… -2, implicating programmed cell death machinery in anoikis. The authors also demonstrated …

Tumor microenvironment: bone marrow-mesenchymal stem cells as key players

P Barcellos-de-Souza, V Gori, F Bambi… - … (BBA)-Reviews on Cancer, 2013 - Elsevier
… These molecular mechanisms are similar to the leukocyte … released by tumors as well as
the molecular mechanisms … key players in the tumor microenvironment scenario, which range …

[HTML][HTML] Tumor microenvironment responsive drug delivery systems

Q He, J Chen, J Yan, S Cai, H Xiong, Y Liu… - Asian journal of …, 2020 - Elsevier
… Recently, tumor cellular molecules-triggered DDSs have … different tumor microenvironments
for a more efficient tumor targeting, … progresses on smart tumor environment responsive drug …

Tumor microenvironment-mediated chemoresistance in breast cancer

N Samadi, B Barazvan, JS Rad - The Breast, 2016 - Elsevier
… Regardless of tumor-microenvironment pathways and their … diversity of molecular properties
of breast cancer also behave … further understand the machinery of resistance in solid tumors. …