Cellular senescence: Molecular mechanisms and pathogenicity

W Wei, S Ji - Journal of cellular physiology, 2018 - Wiley Online Library
… Studies on the molecular mechanisms of cellular senescence are just coming to light. …
roles of other signaling pathways in the induction of cellular senescence, such as c-Jun N-terminal …

Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence

PD Adams - Molecular cell, 2009 - cell.com
Cellular senescence is a proliferation arrest that is typically irreversible … cellular stresses,
including excess rounds of cell division and cancer-causing genetic alterations. Senescence

Molecular mechanisms of cellular senescence

T Becker, S Haferkamp - Senescence and Senescence-Related …, 2013 - books.google.com
… or func‐tional peptides thereof initiated cell cycle arrest and senescent features [46, 47]. In
… a cellular senescence program in melanoma cells and this disability to promote senescence

Mechanisms and functions of cellular senescence

N Herranz, J Gil - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
senescence-associated secretory phenotype (SASP) (Figure 1). Here, we review the molecular
mechanisms controlling cellular senescence … and characterizing senescent cells in vivo. …

Mechanisms and regulation of cellular senescence

L Roger, F Tomas, V Gire - International journal of molecular sciences, 2021 - mdpi.com
Cellular senescence entails a state of an essentially irreversible proliferative … senescence-associated
secretory phenotype. There are different types of senescent cells, and senescence

ROS, cell senescence, and novel molecular mechanisms in aging and age‐related diseases

P Davalli, T Mitic, A Caporali… - … medicine and cellular …, 2016 - Wiley Online Library
… on ROS ability of inducing cell senescence through novel mechanisms that underpin aging
… the novel mechanisms of ROS involvement in epigenetic regulation of cell senescence and …

Molecular mechanisms of cellular senescence in neurodegenerative diseases

HJ Lee, YS Yoon, SJ Lee - Journal of molecular biology, 2023 - Elsevier
molecules via senescence-associated secretory phenotype (SASP). In this review, we
discuss how cellular senescence … and cellular senescence. Finally, we discuss the potential of …

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

R Di Micco, V Krizhanovsky, D Baker… - … reviews Molecular cell …, 2021 - nature.com
… the mechanisms and modulators of cellular senescence establishment and induction of a
senescence-… The molecular mechanisms that determine the choice between apoptosis and …

Vascular ageing and endothelial cell senescence: molecular mechanisms of physiology and diseases

C Regina, E Panatta, E Candi, G Melino… - Mechanisms of ageing …, 2016 - Elsevier
… have been described to control ageing-related endothelial cell senescence including … the
major mechanisms involved in endothelial cell senescence. We also underline key molecular

Cellular senescence in knee osteoarthritis: molecular mechanisms and therapeutic implications

J Xie, Y Wang, L Lu, L Liu, X Yu, F Pei - Ageing research reviews, 2021 - Elsevier
… the role of different cell types of cellular senescence in OA, … of molecular mechanisms of
senescence and OA: regulation of the senescence-associated secretory phenotype of senescent