[HTML][HTML] Molecular mechanisms of hepatic apoptosis

K Wang - Cell death & disease, 2014 - nature.com
… Interventions for hepatic apoptosis alleviate liver injury as demonstrated by pre-clinical
models and clinical trials. The regulation of hepatic apoptosis affects the progression of liver …

Molecular mechanisms of hepatic apoptosis regulated by nuclear factors

K Wang - Cellular signalling, 2015 - Elsevier
Apoptosis is a prominent characteristic in the pathogenesis of liver disease. The mechanism
of hepatic apoptosis is not well understood. Hepatic apoptosis alters relative levels of …

Apoptosis in hepatic pathophysiology

T Patel - Clinics in Liver disease, 2000 - Elsevier
… models of liver apoptosis, for … the molecular mechanisms mediating cell death indicates a
central role for mitochondrian and common cellular mechanisms in mediating both apoptosis

Cellular and molecular mechanisms of liver injury

H Malhi, GJ Gores - Gastroenterology, 2008 - Elsevier
… cell apoptosis leads to slowing and resolution of apoptosis. This review summarizes recent
cellular and molecular advances in the understanding of the injury mechanisms leading to …

Pathophysiological significance of hepatic apoptosis

K Wang, B Lin - International Scholarly Research Notices, 2013 - Wiley Online Library
hepatic apoptosis is different from hepatocyte apoptosis. The hepatocyte apoptosis describes
the apoptotic … liver cells), but the hepatic apoptosis reflects the interaction of manifold cells …

Hepatic fibrosis: molecular mechanisms and drug targets

S Lotersztajn, B Julien, F Teixeira-Clerc… - Annu. Rev …, 2005 - annualreviews.org
… the way for the design of new molecules interfering with regulatory pathways in fibrogenic
cells. This review highlights recent advances in the molecular mechanisms of liver fibrosis and …

Molecular mechanisms of alcohol-induced hepatic fibrosis

SV Siegmund, S Dooley, DA Brenner - Digestive diseases, 2006 - karger.com
… on the molecular mechanisms contributing to alcohol-induced liver fibrosis and cirrhosis as
well as on novel molecularHepatic stellate cell apoptosis and reduced hepatic expression of …

Molecular mechanisms of hepatic fibrogenesis

CJ Parsons, M Takashima… - … of gastroenterology and …, 2007 - Wiley Online Library
… It is well established that the activated hepatic stellate cell (HSC) is the primary cell type …
hepatic fibrosis, it is believed that a comprehensive understanding of the molecular mechanisms

Molecular mechanism of hepatic steatosis: pathophysiological role of autophagy

K Wang - Expert reviews in molecular medicine, 2016 - cambridge.org
… macrolipophagy in response to starvation and hepatic overabundance of TG in obesity. …
apoptotic pathways. There is distinctive relationship between hepatic autophagy and apoptosis, …

Explore the molecular mechanism of apoptosis induced by tanshinone IIA on activated rat hepatic stellate cells

TL Pan, PW Wang - Evidence‐Based Complementary and …, 2012 - Wiley Online Library
… IIA could induce apoptosis of rat HSC-T6 cells [20], the drug targets and … mechanisms
remain to be explored. In this study, we evaluated the apoptotic effect and molecular mechanisms