… model for thyroid carcinoma has not been proven, but evidence suggests that an evolutionary
molecular process is involved, especially in the development of follicular thyroid cancers …

… Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis … pathways and related molecular derangements. …

… ongoing phase II trials of BAY 43-9006 (Sorafenib) in anaplastic thyroid carcinoma and
metastatic medullary thyroid carcinoma are yet to be released. It will be important to find whether …

… and undifferentiated (anaplastic) thyroid carcinomas. Germline mutations of RET are
responsible for the development of heritable forms of medullary thyroid carcinoma (MTC) while …

… The molecular pathogenesis of ATC includes mutations in BRAF, RAS, catenin (cadherin-associated
protein), beta 1, PIK3CA, TP53, AXIN1, PTEN, and APC genes, and chromosomal …

… molecular markers and tools. Based on hypothesis-driven research, the classic view of thyroid
cancer pathogenesis considers thyroid carcinomas … to well-differentiated carcinomas, such …

… years in understanding the molecular biology of thyroid cancer. Various somatic … of thyroid
carcinomas have been discovered [1-4]. Our rapidly expanding knowledge of the molecular …

… Therefore, this review focuses on molecular pathogenesis of PTC, especially among … In
PTCs, the major difference in molecular pathogenesis between childhood and adult cases lies in …

… of thyroid tumor progression as in colorectal cancer (Fearon et al., 1990). We give herein a
synthetic overview of the molecular genetics of thyroid … Thyroid carcinomas are infrequent …

… Although the mortality rate for thyroid cancer is relatively low, … understanding of its
molecular pathogenesis is needed. … mutation in papillary thyroid carcinomas and thyroid tumor …