… Dedifferentiated chondrosarcomas primarily develop as the central subtype, … dedifferentiated
chondrosarcomas. These peripheral cases typically arise from low-grade chondrosarcomas …

… Chondrosarcoma (CHS) belongs to a broad group of … of CHS comprehensively from its
molecular basics, through diagnosis, … dedifferentiated CHS is negative for S100 in dedifferentiated …

… Dedifferentiated chondrosarcoma is a rare adult bone tumor with a dismal … chondrosarcoma
juxtaposed to high-grade nonchondrogenic sarcoma. Dedifferentiated chondrosarcomas …

… In conclusion, the molecular genetic characterization of this case of dedifferentiated
chondrosarcoma provides strong evidence for a monoclonal origin, since both components share an …

… of dedifferentiation in peripheral secondary chondrosarcoma (CS), although the molecular
… to differ from those involved in the process of dedifferentiation of central CS. PDGFRβ could …

… Subtypes of CHSs, such as dedifferentiated, mesenchymal, and clear cell CHSs are also
presented. In addition, we introduce updated cytogenetic and molecular genetic findings to …

… In this study, we show for two cases that the cartilaginous and the anaplastic component of
dedifferentiated chondrosarcomas carry identical mutations, together with the relatively rare …

… pathology to make a precise diagnosis. In addition, the … molecular mechanisms of
chondrosarcoma dedifferentiation … analysis of cell cycle-related molecules. p53 plays a role in cell …

… and molecular lesions that enable surgical pathologists to … types begins with dedifferentiated
chondrosarcoma, the … of both differentiated and dedifferentiated chondrosarcoma, and will …

… Pathologists should be aware of their existence to avoid confusion with clear cell
chondrosarcoma, dedifferentiated chondrosarcoma, or chondroblastic osteosarcoma. …