… Metastasis is the hallmark of cancer that is responsible for the greatest number of cancer-related
deaths. Yet, it remains poorly understood. The continuous evolution of cancer biology …

… of circRNAs implicated in cancer hallmark molecular signaling. First, … molecular functions.
Subsequently, we summarize the roles of circRNAs in the framework of each cancer hallmark …

… of each hallmark as described … hallmark capabilities, two new emerging hallmark capabilities,
the constitution and signaling interactions of the tumor microenvironment crucial to cancer …

… same hallmark molecular pathways and networks. For this reason, it is likely that successful
… of cancer genomes will require comprehensive knowledge of the molecular networks under …

… Taken together, the classic breast tumor molecular subtypes are defined by hormonal and
growth receptors according to the most prominent cancer hallmark, ie, 'sustaining proliferative …

… As we noted at the time, these hallmark traits, on their own, fail to address the complexities
of cancer pathogenesis, that is, the precise molecular and cellular mechanisms that allow …

… Herein, we propose that the molecular logic behind the conversion of non-CSCs into
CSCs can be better understood in terms of cellular metabotypes that operate as pathways or …

… by inflammatory conditions which predispose to cancer). Smouldering inflammation is a …
hallmark of cancer. Key orchestrators at the intersection of the intrinsic and extrinsic pathways …

… and molecular biological tools, studies in cancer … pathways (Hallmarks 3 and 4) in the
middle. Finally, long-ranging effects of metabolic reprogramming on the cancer cell itself (Hallmark …

… , but many molecules and signaling pathways relevant to VM … the context of stresses facing
cancer cells (Hallmark B), again … Vascularization is certainly a hallmark of cancer development…