… Using unsupervised consensus clustering of quantitative imaging phenotypes of the tumor
… show that imaging phenotypes may be used to infer dysregulated molecular pathways that …

… To map imaging subtypes to particular molecular signaling pathways, we performed SAM
on pathway activity estimates derived from the analysis of TCGA tumor CNV and gene …

… digital transcript imaging enables simultaneous monitoring of the entire pathway reporter
gene … We show that molecular phenotyping allows fast and accurate pathway delineation in …

… samples, it is not always apparent from the imaging phenotype. … image phenotypes with
RNA signatures captured by metagenes and how they are associated with molecular pathways. …

… drivers of these imaging phenotypes remain largely unknown. An Imaging-Genomics analysis
… MRI derived quantitative volumetric tumor phenotype features and molecular pathways. …

… , and distinguish phenotypes such as estrogen receptor status and p53 mutation state.
Pathways identified through this analysis perform as well or better than phenotypes used in the …

… Pathway analysis methodologies couple traditional gene expression … molecular pathway
networks, offering a promising approach towards the biological interpretation of phenotype …

… molecular phenotypes from whole-slide histopathology images using human-interpretable
image … that can exhaustively map whole-slide images at two and four micron-resolution. Cell- …

… research area called “molecular imaging”, “imaging genomics”, … molecular properties of
tumors and their imaging phenotypes. … significant correlations of molecular markers and clinical …

… -associated proteins and phenotypes has improved our knowledge of ciliary functions. In
particular, investigating ciliopathies has helped us to understand the molecular mechanisms by …