… to play important roles in many normal physiological functions and to be involved in a variety
… This discovery highlights these orphan receptors as potential new molecular targets for CBD…

… important in yeast resistance to five different pro-oxidants did not yield a large number of
DNA repair functions, suggesting that DNA is not the primary target [5]. Furthermore, analysis of …

… of predictable and therapeutically promising molecular targets. RNAi technology has progressed
… Initial observations that were useful for studying gene function in worms were quickly …

… For now, such information covers only a tiny fraction of the full network and is biased towards
certain biological functions. For example, protein interactions in the literature curated by …

… Because of their diverse biological functions, aberrations in STAT signaling are predicted
to … activity and biological functions of some STATs by using small molecule mimics of …

… However, only a few types of cucurbitacins were examined in depth, and even fewer of their
molecular targets were identified. Current advances provide evidence that fibrous-actin (F-…

… E7 polypeptide to inactivate multiple molecules of cellular target proteins. The relatively
low … that target pRB, high-risk HPVs also encode a second function, E6, which subverts p53 …

… Historically, the function of PTEN has 2860 been described as a phosphatase that … new
lines of evidence suggest that it may have other biologic functions (53, 170). There is strong …

… Target miRNAs are involved in regulation of different biological functions. … , metabolism),
their physiological effects, and the identification of their cellular and molecular targets. …

… of HMGA proteins are direct downstream targets of numerous signal transduction pathways
… biological features allows the HMGA proteins to serve as central ‘hubs’ of nuclear function. …