… to potential clinical trial design is the fact that the pattern of MET copy-number alteration in
gastric cancer (… in gastric cancer has been successful using both small-molecule TKIs and …

… development as a drug target if it is present … potential target molecule should therefore be
analyzed for its role in carcinoma cell formation and in acquisition of cancer-related molecular …

… We focus on those that have the greatest potential for rapid emergence into clinical trials
based on availability, clinical use, anticipated plasma concentrations, and toxicologic spectrum. …

… and potential molecular markers that could help to improve the strategies for breast cancer
therapy. … A standardized dataset called the TCGA Pan-Cancer Clinical Data Resource was …

… cancer subtypes has led to many new molecular targets for … As a result, a range of novel
targeted molecular therapeutic … full clinical potential is still being explored in early-phase clinical …

… Cancer, more than any other human disease, now has a surfeit of potential molecular targets
… Currently, a number of attractive and validated cancer targets remain outside of the reach of …

… The involvement of NFκB in skin cancer and … the molecular link bridging inflammation and
cancer. As a result, NFκB becomes an ideal molecular target in controlling cancer development…

Purpose To compare the progression-free survival (PFS) using a treatment regimen selected
by molecular profiling (MP) of a patient's tumor with the PFS for the most recent regimen on …

… Summary of potential molecular targets and therapeutic agents. Potential molecular targets
include receptor tyrosine kinases and intracellular signaling molecules, which promote tumor …

… Clinical trials indicated that curcumin has no dose-limiting toxicity, and therefore, it has
enormous potential for the prevention and treatment of cancer [138,166]. Potential activity of …