Ketogenic diet in cancer prevention and therapy: molecular targets and therapeutic opportunities

WH Talib, AI Mahmod, A Kamal, HM Rashid… - … issues in molecular …, 2021 - mdpi.com
… The ketogenic diet (KD), a high-fat and very-… ketogenic diet’s therapeutic mechanisms in
cancer treatment. This review highlights the crucial mechanisms that explain the ketogenic diet’s …

Molecular mechanisms underlying the bioactive properties of a ketogenic diet

M Murakami, P Tognini - Nutrients, 2022 - mdpi.com
… act as energy substrates, signaling molecules, and epigenetic … findings on the molecular
mechanisms of a ketogenic diet and … molecular basis of the bioactive effects of a ketogenic diet

[PDF][PDF] The ketogenic diet: from molecular mechanisms to clinical effects

J Freeman, P Veggiotti, G Lanzi, A Tagliabue… - Epilepsy Res, 2006 - academia.edu
… Within the last decade, several putative molecular targets and novel insights have emerged.
Not surprisingly, given all of the metabolic, physiological and hormonal changes induced by …

Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet regimen
that mimics the metabolism of the fasting state to induce the production of ketone bodies…

Mechanisms of action of antiseizure drugs and the ketogenic diet

MA Rogawski, W Löscher… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
… The ketogenic diet is one treatment option for drug-resistant … more of a diverse set of molecular
targets in the brain. ASDs act … The ketogenic diet leads to increases in circulating ketones, …

The ketogenic diet revisited: beyond ketones

J Sourbron, K Thevissen, L Lagae - Frontiers in neurology, 2021 - frontiersin.org
… options, and therapies that target multiple mechanisms are likely to … dietary treatments,
such as the ketogenic diet (KD), are valuable alternative options (5–7). Initial studies with dietary

Lysosomal acid lipase as a molecular target of the very low carbohydrate ketogenic diet in morbidly obese patients: the potential effects on liver steatosis and …

S Ministrini, L Calzini, E Nulli Migliola, MA Ricci… - Journal of clinical …, 2019 - mdpi.com
… Safety of ketogenic diets has been largely discussed in the literature. Most of the existing …
who are usually treated with normocaloric ketogenic diets for long periods; this notwithstanding …

Ketogenic diet in the treatment of gliomas and glioblastomas

S Dal Bello, F Valdemarin, D Martinuzzi, F Filippi… - Nutrients, 2022 - mdpi.com
… In recent years, scientific interest in the use of the ketogenic diet (… speculate which are the
molecular targets of KD used … the possible use of a ketogenic diet as a combination therapy …

Short-term ketogenic diet induces a molecular response that is distinct from dietary protein restriction

KC Kalafut, SJ Mitchell, MR MacArthur… - Frontiers in Nutrition, 2022 - frontiersin.org
… in all mice regardless of diet. While conclusions are … Not Ketogenic, Diets Induce Molecular
Markers of Dietary Protein Restriction Next, we aimed to determine whether ketogenic diets

Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?

TA Simeone, KA Simeone, CE Stafstrom, JM Rho - Neuropharmacology, 2018 - Elsevier
… Although the mechanisms underlying the anti-seizure effects of the high-fat ketogenic diet
(KD… been shown to interact with multiple novel molecular targets such as histone deacetylases, …