Breast cancer: current molecular therapeutic targets and new players

S Nagini - Anti-Cancer Agents in Medicinal Chemistry …, 2017 - ingentaconnect.com
… Schematic diagram showing molecular therapeutic targets and signaling pathways involved
in breast cancer. Therapeutic targets and their specific inhibitory compounds discussed in …

Emerging molecular therapeutic targets for cholangiocarcinoma

S Rizvi, GJ Gores - Journal of hepatology, 2017 - Elsevier
therapeutic implications as it is well-known that gain of function mutations are potential
therapeutic targets in … relevance makes these mutations an important potential therapeutic target. …

Molecular therapeutic targets in inflammation: cyclooxygenase and NF-κB

T Krakauer - Current Drug Targets-Inflammation & Allergy, 2004 - ingentaconnect.com
… Thus, NF-κB activation represents an attractive therapeutic target in suppressing … Thus,
the gene expression approach could also provide new pathways or molecules as drug targets. …

Molecular therapeutic target for type-2 diabetes

KC Chou - Journal of Proteome Research, 2004 - ACS Publications
… In view of this, GFAT and its interaction mechanism with UDP-GlcNAc may become a novel
therapeutic target for the treatment of type 2 diabetes. To stimulate the structure-based drug …

The role of signaling pathways in cervical cancer and molecular therapeutic targets

J Manzo-Merino, A Contreras-Paredes… - Archives of medical …, 2014 - Elsevier
Molecular pathways that participate in cervical malignant transformation have emerged as
promising directed therapeutic targets. In this review, we explore some of the major pathways …

Molecular therapeutic targets in non-small cell lung cancer

K Sankar, SM Gadgeel, A Qin - Expert review of anticancer therapy, 2020 - Taylor & Francis
therapeutic targets of FGFR can thus be crucial in identifying therapies for squamous cell
histology and in those who acquire resistance to other therapeutic targets [Citation95]. …

Cellular and molecular therapeutic targets in inflammatory bowel disease—focusing on intestinal barrier function

I Schoultz, ÅV Keita - Cells, 2019 - mdpi.com
… This review will focus on the main cell types and molecular features involved in IBD. We
will discuss cellular and molecular targets and how current and potential therapies have been …

Therapeutic targets: progress of their exploration and investigation of their characteristics

CJ Zheng, LY Han, CW Yap, ZL Ji, ZW Cao… - Pharmacological …, 2006 - ASPET
… There are 1535 targets collected in the therapeutic target database compared with ∼500
targets reported in a 1996 review. Knowledge of these targets is helpful for molecular

[HTML][HTML] Molecular pathways and therapeutic targets in lung cancer

E Shtivelman, T Hensing, GR Simon, PA Dennis… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Lung cancer is still the leading cause of cancer death worldwide. Both histologically and
molecularly lung cancer is heterogeneous. This review summarizes the current knowledge of …

Molecular therapeutic targets for glioma angiogenesis

S Takano, T Yamashita, O Ohneda - Journal of oncology, 2010 - Wiley Online Library
Due to the prominent angiogenesis that occurs in malignant glioma, antiangiogenic therapy
has been attempted. There have been several molecular targets that are specific to …