… The 21 β-lactam antibiotics subject to TDM across the various ICUs are shown in Figure 1.
The number of β-lactams monitored by a single centre ranged between 3 and 12 (mean 7). All …

… The SENTRY Program has monitored pathogen frequency and antimicrobial resistance
patterns of nosocomial and community-acquired infections through sentinel hospitals world wide…

… hydrolyzing their beta-lactam ring. Currently, CTX-M beta-lactamases represent the most
widespread … Among the AmpC beta-lactamases, CMY represents by far the most frequent beta-…

… binding, and the associated change in unbound β-lactam concentrations, 16 despite the
high … of unbound β-lactam antibiotic concentration targets in a TDM programme in critically ill …

… Monitoring for consecutive years allows close observation for the detection of trends in …
species confer resistance to β-lactams, (including extended-spectrum β-lactams, β-lactam/…

… The objectives of this study were to determine the genetic basis of beta-lactam resistance
and … We screened for the presence of five beta-lactam resistance gene families (bla CMY , bla …

… in this investigation as part of the Study for Monitoring Antimicrobial Resistance Trends.
Antimicrobial susceptibility and extended-spectrum beta-lactamase (ESBL) rates among the …

… through β-lactam protection with β-lactamase inhibitors and/or … with β-lactams is the use of
therapeutic drug monitoring (TDM) … In this review, we examine the evidence for β-lactam TDM, …

… Because of the rapid emergence of metallo-β-lactamase types and dissemination … to
include local monitoring of multidrug-resistant Gram-negative bacilli. Such programs can guide …

… MYSTIC Program highlight the importance of monitoring the resistance of Enterobacteriaceae
to antimicrobial agents, and in particular, the prevalence of ESBL- and AmpC β-lactamase…