A noninterventional study evaluating the effectiveness and safety of lacosamide added to monotherapy in patients with epilepsy with partial‐onset seizures in daily …

U Runge, S Arnold, C Brandt, F Reinhardt, F Kühn… - …, 2015 - Wiley Online Library
safety of adjunctive lacosamide in the treatment of partial‐onset seizures ( POS ) was gained
during placebo‐controlled clinical trials in patients … of adjunctive lacosamide added to one …

Long‐term safety and efficacy of lacosamide and controlled‐release carbamazepine monotherapy in patients with newly diagnosed epilepsy

E Ben‐Menachem, HP Grebe, K Terada, L Jensen… - …, 2019 - Wiley Online Library
Monotherapy approval of lacosamide in the EU was based on the results of a large-scale,
double-blind trial, which demonstrated that lacosamide … first-line monotherapy in patients with …

Long‐term safety and tolerability of lacosamide monotherapy in patients with epilepsy: Results from a multicenter, open‐label trial

E Ben‐Menachem, J Dominguez, J Szász… - Epilepsia …, 2021 - Wiley Online Library
patient taking lacosamide 200 mg/day as monotherapy had a positive pregnancy test and
stopped taking lacosamide … One patient taking lacosamide 400 mg/day as monotherapy had a …

[HTML][HTML] Long-term efficacy and safety of lacosamide monotherapy in the treatment of partial-onset seizures: a multicenter evaluation

BG Giráldez, R Toledano, I García-Morales… - Seizure, 2015 - Elsevier
… We report clinical outcomes of lacosamide monotherapy in patients with focal epilepsy…
lacosamide (LCM) monotherapy, as first-line and conversion regimens, in the treatment of patients

Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3 …

M Baulac, F Rosenow, M Toledo, K Terada… - The Lancet …, 2017 - thelancet.com
… Our findings suggest that lacosamide is a suitable option for first-line monotherapy in patients
… adjunctive trials of antiepileptic drugs might be extrapolated to the monotherapy setting. …

Long-term efficacy and safety of lacosamide and levetiracetam monotherapy in elderly patients with focal epilepsy: a retrospective study

C Del Bianco, F Placidi, C Liguori, L Mari, M Ulivi… - Epilepsy & Behavior, 2019 - Elsevier
patients with epilepsy while lacosamide (LCM), which has been recently approved in European
Union (EU) as monotherapy … of LCM as monotherapy in elderly patients affected by focal …

Lacosamide monotherapy in clinical practice: A retrospective chart review

V Villanueva, BG Giráldez, M Toledo… - Acta Neurologica …, 2018 - Wiley Online Library
… Retrospective, non-interventional chart review of lacosamide monotherapy patients aged
≥16 years in Europe. Outcomes included retention rate at observational point (OP) 3 (12 ± 3 …

[HTML][HTML] Lacosamide monotherapy for partial onset seizures

S Lattanzi, C Cagnetti, N Foschi, L Provinciali… - Seizure, 2015 - Elsevier
… We prospectively followed-up consecutive patients converted to lacosamide monotherapy
-year efficacy and safety of oral lacosamide as conversion monotherapy in adults patients with …

The efficacy of lacosamide as monotherapy and adjunctive therapy in focal epilepsy and its use in status epilepticus: clinical trial evidence and experience

S Bauer, LM Willems, E Paule… - Therapeutic …, 2017 - journals.sagepub.com
… better seizure control for some of these patients [Luciano and Shorvon, 2007; … safety profile
are needed for use as initial monotherapy as they might be continued for decades in patients

A long-term noninterventional safety study of adjunctive lacosamide therapy in patients with epilepsy and uncontrolled partial-onset seizures

BJ Steinhoff, K Eckhardt, P Doty, M De Backer… - Epilepsy & Behavior, 2016 - Elsevier
safety and efficacy of lacosamide in more than 1300 patients with POS, each randomized to
receive 200, 400, or 600 mg/day lacosamide … Five patients took lacosamide as monotherapy