Circadian genes, rhythms and the biology of mood disorders

CA McClung - Pharmacology & therapeutics, 2007 - Elsevier
… of these genes in brain regions and neurotransmitter systems associated with mood regulation
… In this review, the evidence linking circadian rhythms and mood disorders, and what is …

The circadian basis of mood disorders: recent developments and treatment implications

P Monteleone, M Maj - European Neuropsychopharmacology, 2008 - Elsevier
… and mood disorders, and, finally, we discuss strategies for manipulating (disturbed) circadian
… in certain circadian genes that associate with mood disorders and, in particular, bipolar …

Disruption of the circadian timing systems: molecular mechanisms in mood disorders

J Mendlewicz - CNS drugs, 2009 - Springer
circadian genes and mood disorders. These data demonstrate that several clock genes
have been implicated in susceptibility to mood disorders, disease recurrence and the circadian

Circadian neurogenetics of mood disorders

J Mendoza, G Vanotti - Cell and tissue research, 2019 - Springer
… states, although their specific circadian role is not fully known. In mood disorders, alterations
of the … Thus, functional expression of circadian genes in the brain is compromised in mood

Cellular circadian clocks in mood disorders

MJ McCarthy, DK Welsh - Journal of biological rhythms, 2012 - journals.sagepub.com
… In considering this new evidence, we conclude that if clock gene defects cause mood
disorders, the SCN may not be the affected brain region, and focusing on this region may obscure …

Genetics of circadian rhythms and mood spectrum disorders

B Etain, V Milhiet, F Bellivier, M Leboyer - European …, 2011 - Elsevier
… The study of circadian phenotypes and circadian genes in mood spectrum … factors for
mood disorders and may prevent circadian rhythms from properly adapting to external cues. …

Significant role of genegene interactions of clock genes in mood disorder

M Park, SA Kim, J Yee, J Shin, KY Lee… - … of Affective Disorders, 2019 - Elsevier
… possible genetic interactions among circadian function genes in the context of mood disorder.
… We hypothesized that circadian genes contribute significantly to mood disorders, and that …

Chronobiology and mood disorders

A Wirz-Justice - Dialogues in clinical neuroscience, 2003 - Taylor & Francis
… role of circadian rhythms in mood disorders, or … mood, energy, appetite, and sleep. Future
studies will elucidate any allelic mutations in “circadian clock” –related or “sleep”-related genes

… association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder

V Soria, E Martinez-Amoros, G Escaramís… - …, 2010 - nature.com
circadian rhythms have been described in mood disorders (MD), but the involvement of genetic
variation in genes … Our data support the contribution of the circadian system to the genetic

Prospects for circadian treatment of mood disorders

A Hühne, DK Welsh, D Landgraf - Annals of medicine, 2018 - Taylor & Francis
… Similarly, BD has been linked to polymorphisms of clock genes [Citation15], … genes together
as a system has tended to confirm an association between clock genes and mood disorders […