Morphine withdrawal‐induced morphological changes in the nucleus accumbens
S Spiga, MC Puddu, M Pisano… - European Journal of …, 2005 - Wiley Online Library
… the emergence of morphine withdrawal, viewed as a phase of opiate dependence (… morphine
withdrawal, both spontaneous and pharmacologically precipitated with the classic µ-opiate …
withdrawal, both spontaneous and pharmacologically precipitated with the classic µ-opiate …
Persistent and reversible morphine withdrawal‐induced morphological changes in the nucleus accumbens
… Thus, in the present article we sought to determine if morphine withdrawal-induced
spines' alteration of MSN in the subdivisions of the NAcc would persist over time and would …
spines' alteration of MSN in the subdivisions of the NAcc would persist over time and would …
Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell
R Sharf, M Sarhan, RJ DiLeone - Biological psychiatry, 2008 - Elsevier
… morphine withdrawal. To understand better the neuroanatomic basis of orexin in morphine
withdrawal… responses to naloxone-precipitated morphine withdrawal in the VTA, Acb, and LC, …
withdrawal… responses to naloxone-precipitated morphine withdrawal in the VTA, Acb, and LC, …
Increased opioid inhibition of GABA release in nucleus accumbens during morphine withdrawal
B Chieng, JT Williams - Journal of Neuroscience, 1998 - Soc Neuroscience
… in the nucleus accumbens during withdrawal. Interneurons of the nucleus accumbens
play a key role in the integration of afferent input and regulation of the output of the nucleus (…
play a key role in the integration of afferent input and regulation of the output of the nucleus (…
Nucleus accumbens D2-and D1-receptor expressing medium spiny neurons are selectively activated by morphine withdrawal and acute morphine, respectively
T Enoksson, J Bertran-Gonzalez, MJ Christie - Neuropharmacology, 2012 - Elsevier
… ► D2R and D1R-GFP transgenics can identify activated (c-Fos) nucleus accumbens
neurons. ► Both opioid withdrawal and acute morphine induce c-Fos in nucleus accumbens. ► …
neurons. ► Both opioid withdrawal and acute morphine induce c-Fos in nucleus accumbens. ► …
Involvement of D2 dopamine receptors in the nucleus accumbens in the opiate withdrawal syndrome
GC Harris, G Aston-Jones - Nature, 1994 - nature.com
… the ability of dopamine agonists to alleviate withdrawal (n = 5, P= … nucleus accumbens, we
microinjected R-NPA (1-10 pg) into the accumbens before naloxone-precipitated withdrawal …
microinjected R-NPA (1-10 pg) into the accumbens before naloxone-precipitated withdrawal …
Nucleus accumbens AMPA receptors are necessary for morphine-withdrawal-induced negative-affective states in rats
SE Russell, DJ Puttick, AM Sawyer… - Journal of …, 2016 - Soc Neuroscience
… morphine dependence to show that GluA1 subunits of AMPA glutamate receptors in the
nucleus accumbens (… for aversive effects of morphine withdrawal. Using biochemical methods in …
nucleus accumbens (… for aversive effects of morphine withdrawal. Using biochemical methods in …
NMDA receptor in nucleus accumbens is implicated in morphine withdrawal in rats
… morphine withdrawal symptoms in rats, (b) it is unlikely that this is due to the interference on
motor functions, (c) NMDA receptors in nucleus accumbens, … inhibiting morphine withdrawal …
motor functions, (c) NMDA receptors in nucleus accumbens, … inhibiting morphine withdrawal …
Repeated morphine exposure decreased the nucleus accumbens excitability during short‐term withdrawal
LJ Heng, J Yang, YH Liu, WT Wang, SJ Hu, GD Gao - Synapse, 2008 - Wiley Online Library
… However, the cellular neuroadaptations that take place in accumbens neurons after … how
nucleus accumbens neuronal excitability becomes affected in rats exposed to morphine using …
nucleus accumbens neuronal excitability becomes affected in rats exposed to morphine using …
Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal
… nucleus accumbens were made dependent on morphine by subcutaneous implantation of
two 75-mg morphine … the region of the nucleus accumbens the most sensitive. Observational …
two 75-mg morphine … the region of the nucleus accumbens the most sensitive. Observational …
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