… to sensorimotor integration and motor learning [3, 4]. In this study, we generated mice carrying
an … Homozygous R552H mice show severe reductions in cerebellar growth and postnatal …

… PCs (n = 67 from C57BL/6 mice and n = 20 from L7-Ai27 mice) were identified by the presence
of simple and complex spikes, and determined to be from a single unit by confirming that …

… to assess motor ability in mice. We examined a number of inbred strains to determine whether
there is genetic variability in rotorod performance and motor learning. Mice received three …

… approach of motor skills and motor learning during aging in Lurcher mutant mice, we …
equilibrium maintenance and motor learning. Moreover, in these mutants, we showed that …

… , its involvement in motor learning remains unclear. To examine the role of striatal NMDAR
in motor learning, we created striatum-specific NMDAR1 subunit knockout mice, analyzed the …

… onset of the motor learning deficit and the lack of overt dystonia in our mice will require
additional study. It will be of interest to determine whether our transgenic mice have distinct …

… we hypothesized that the motor learning deficits in cerebellar KO mice originate from the
loss of Mecp2 in excitatory granule cells, inhibitory Purkinje cells, and/or molecular layer …

… forebrain cholinergic neurons after learning does not affect task … cortical motor centers during
coordinated motor learning. … motor areas, medial prefrontal cortex (mPFC) and motor cortex, …

… we show that there is no motor learning impairment in these mutant mice that lack PF-PC
LTD. These findings demonstrate that PF-PC LTD is not essential for cerebellar motor learning. …

… The present data are consistent with the hypothesis that the impairment of mutant mice … mice
may result from a motor learning impairment. That is, the mutant mice have difficulty learning …