Inducible ablation of dopamine D2 receptors in adult mice impairs locomotion, motor skill learning and leads to severe parkinsonism

EP Bello, R Casas-Cordero, GL Galiñanes… - Molecular …, 2017 - nature.com
… To determine the importance of D2R in motor learning, we trained mice from all groups to
negotiate an accelerated rotarod in a 3 trials per day schedule performed during 5 consecutive …

Learning-dependent potentiation in the vibrissal motor cortex is closely related to the acquisition of conditioned whisker responses in behaving mice

J Troncoso, A Múnera… - Learning & Memory, 2007 - learnmem.cshlp.org
… -protracting responses in alert behaving mice. This learning-dependent potentiation, which
… and whisker-pad EMG amplitude during motor learning acquisition, was related to an …

[HTML][HTML] Impaired motor coordination and learning in mice lacking anoctamin 2 calcium-gated chloride channels

F Neureither, K Ziegler, C Pitzer, S Frings, F Möhrlen - The Cerebellum, 2017 - Springer
… from Ano2 −/− mice, a mouse line that was previously … motor coordination deficits that
constitute a condition of mild ataxia. Moreover, motor learning is severely impaired in Ano2 −/− mice

Motor training improves coordination and anxiety in symptomatic Mecp2-null mice despite impaired functional connectivity within the motor circuit

Y Yue, P Xu, Z Liu, X Sun, J Su, H Du, L Chen… - Science …, 2021 - science.org
… Our evidence supports a model in which motor learning strengthens the connectivity of a
subgroup of neurons for storing information while decreasing connectivity among the rest of the …

Abnormal nuclear envelope in the cerebellar Purkinje cells and impaired motor learning in DYT11 myoclonus-dystonia mouse models

F Yokoi, MT Dang, G Yang, JD Li, A Doroodchi… - Behavioural brain …, 2012 - Elsevier
… (Sgce pKO) mice. Sgce pKO mice showed motor learning deficits, while they did not show
abnormal nuclear envelope in the cerebellar Purkinje cells, robust motor deficits, or myoclonus…

qMotor, a set of rules for sensitive, robust and quantitative measurement of motor performance in mice

LM Luh, I Das, A Bertolotti - Nature protocols, 2017 - nature.com
… the initial learning period, rotarod analyses measure motor … the motor learning phase to
allow quantitative assessment of … prevents motor and molecular defects in a transgenic mouse

[HTML][HTML] Location-and sex-specific differences in weight and motor coordination in two commonly used mouse strains

AD Kovács, DA Pearce - Scientific reports, 2013 - nature.com
… exclusively on the 5010 or 2018 diet in Sioux Falls restored motor learning we used two
consecutive rotarod tests. Surprisingly, only males kept on the 5010 diet and females kept on the …

Disruption of the dopamine Β-hydroxylase gene in mice suggests roles for norepinephrine in motor function, learning, and memory.

SA Thomas, RD Palmiter - Behavioral neuroscience, 1997 - psycnet.apa.org
Motor Learning and Performance Motor learning and function in DBH —/— mice appeared
… This was manifest as an inability to swim for some mice and a reduction in swim speed for …

[HTML][HTML] Are we ready for a natural history of motor learning?

L Shmuelof, JW Krakauer - Neuron, 2011 - cell.com
… First, we hope to show that explicit comparison of motor learning results across the various
model systems … Finally, given that neurorehabilitation is predicated on motor learning ( …

Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice

C Chen, M Kano, A Abeliovich, L Chen, S Bao, JJ Kim… - Cell, 1995 - cell.com
… for discrete motor learning. In the present study, we have analyzed the mutant mice deficient
in … mutant mice remain multiply innervated by CFs. In this paper, we report that these mutant …