… Results of the present study showed that Lurcher mutant mice were able to learn a
sensorimotor task and to adopt an adapted walking behavior on the rotorod, which agrees with …

… that lurcher mutants have spared abilities in terms of motor coordination and motor learning.
… In the present study, not only was motor learning not abolished but there was no difference …

… Rather than attempting extensive surgical procedures, we chose to use Lurcher mice, a
strain of mutant mice that completely lacks cerebellar Purkinje cells, making their deficit …

… Motor skills of Lurchers were found to be worse than in wild type mice, but they showed motor
learning … enforced motor activity represented by rotarod training on motor skills and spatial …

… enforced motor training on spatial learning ability and motor coordination in adult Lurcher
mutant mice of the C57Bl strain. Experimental mice were trained repetitively on a rotarod. …

… These results indicate that in spite of an almost total lack of Purkinje cells, postural
sensorimotor learning of a complex type is possible, although the scores achieved by …

… motor learning required … lurcher mutants differ from normal mice in learning to maintain
body balance on a narrow round bridge. It was found that both normal mice and lurcher mutants …

… cerebellum is involved in feedforward motor control mechanisms. In responses requiring
control of posture during climbing, feedforward motor control mechanisms may not be required. …

… of motor abilities in Purkinje cell degeneration (pcd) mice [21], another mouse model of …
learning ability in Lurcher mutant mice but its effect on motor abilities was inconclusive [22]. …

… At this time, tentative identification of the Lurcher mice was based on the presence of the
associated micro-white phenotype (MiWh). The first indications of a deficit in motor control …