Cell competition controls differentiation in mouse embryos and stem cells
M Hashimoto, H Sasaki - Current Opinion in Cell Biology, 2020 - Elsevier
… in early mouse embryos revealed that cell competition is a fundamental process underlying
embryonic development. … Early mouse development is divided into preimplantation and …
embryonic development. … Early mouse development is divided into preimplantation and …
Emerging mechanisms of cell competition
NE Baker - Nature Reviews Genetics, 2020 - nature.com
… .5 and E17.5, and such competition is hypothesized to be required … cell competition in the
liver and the immune system occur post-embryonically, as does cell competition in the mouse …
liver and the immune system occur post-embryonically, as does cell competition in the mouse …
Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
… by cell competition during early mouse development. Using single-cell transcriptional
profiling of eliminated mouse epiblast cells, we identify hallmarks of cell competition and …
profiling of eliminated mouse epiblast cells, we identify hallmarks of cell competition and …
Distinct modes of cell competition shape mammalian tissue morphogenesis
… cell competition switch is physiologically relevant: when it is perturbed, so too is barrier
formation. Our findings show that cell competition … dynamically adjusts cell competition strategies …
formation. Our findings show that cell competition … dynamically adjusts cell competition strategies …
Cell competition in development, homeostasis and cancer
SM van Neerven, L Vermeulen - Nature Reviews Molecular Cell …, 2023 - nature.com
… the plethora of cell competition mechanisms by first distinguishing passive and active
forms of cell competition, whereafter we discuss the different modes of active cell competition. …
forms of cell competition, whereafter we discuss the different modes of active cell competition. …
P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development
S Bowling, A Di Gregorio, M Sancho, S Pozzi… - Nature …, 2018 - nature.com
… a key effector of cell competition in the early mouse embryo, as … of defective cells in
development to promoting the expansion … roles of cell competition during mouse development …
development to promoting the expansion … roles of cell competition during mouse development …
Cell competition during growth and regeneration
… Here, we discuss the existing literature regarding the current landscape of cell competition,
… of cell competition. We further discuss the clinical relevance of cell competition in the …
… of cell competition. We further discuss the clinical relevance of cell competition in the …
Cell competition and its role in the regulation of cell fitness from development to cancer
A Di Gregorio, S Bowling, TA Rodriguez - Developmental cell, 2016 - cell.com
… Subsequently, in mammals it was also found that if c-Myc is overexpressed in a mosaic
fashion during the early stages of mouse development or during the onset of embryonic stem …
fashion during the early stages of mouse development or during the onset of embryonic stem …
Cell competition: Emerging mechanisms to eliminate neighbors
R Nagata, T Igaki - Development, growth & differentiation, 2018 - Wiley Online Library
… cell polarity. Studies on the mechanisms and roles of cell competition have suggested that
cell competition can … The former type of cell competition includes Minute or Myc-induced cell …
cell competition can … The former type of cell competition includes Minute or Myc-induced cell …
[HTML][HTML] Cell competition: A historical perspective
G Morata - Developmental Biology, 2021 - Elsevier
… cell competition, with special emphasis in the history of the phenomenon within the general
frame of Developmental … This work showed that cell competition occurred between cells that …
frame of Developmental … This work showed that cell competition occurred between cells that …
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