过去一年中添加的文章,按日期排序
[HTML][HTML] Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1
A Pereira, J Diwakar, G Masserdotti, S Beşkardeş… - Nature …, 2024 - nature.com
4 天前 - … architecture and DNA methylation in mouse astrocyte-to-neuron reprogramming
mediated by … PmutNgn2 leads to higher reprogramming efficiency and enhances epigenetic …
mediated by … PmutNgn2 leads to higher reprogramming efficiency and enhances epigenetic …
P-159 Single-cell high-throughput methylation and transcriptomic analysis indicates variations in sensitivity to Folate-mediated one-carbon metabolism in mouse …
A Reyes Palomares, A Vincelle-Nieto… - Human …, 2024 - academic.oup.com
5 天前 - … significant progress in IVF embryo culture conditions, the sensitivity to the outer
metabolic environment during the extensive genomic transformation of embryo reprogramming …
metabolic environment during the extensive genomic transformation of embryo reprogramming …
Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells
C Parikh, R Glenn, Y Shi, K Chatterjee, E Swanzey… - bioRxiv, 2024 - biorxiv.org
6 天前 - … mouse stock allow 44 the identification of quantitative trait loci controlling DNA
methylation … during nPSC derivation and maintenance, we used OKSM reprogramming 132 …
methylation … during nPSC derivation and maintenance, we used OKSM reprogramming 132 …
Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis
8 天前 - … associated gene expression signature in AT2 cells, we suppressed DNA methylation
in young wild- 413 type C57BL/6J mice by systemic administration of GSK-3484862, a …
in young wild- 413 type C57BL/6J mice by systemic administration of GSK-3484862, a …
AMPK Deficiency Increases DNA Methylation and Aggravates Colorectal Tumorigenesis in AOM/DSS Mice
Q Sun, Q Tian, A Bravo Iniguez, X Sun, H Zhang… - Genes, 2024 - mdpi.com
11 天前 - … metabolic reprogramming. In this study, wild-type and AMPK knockout mice were
subjected … , tumor size, and hyperplasia in AOM/DSS-treated mice. The aggravated colorectal …
subjected … , tumor size, and hyperplasia in AOM/DSS-treated mice. The aggravated colorectal …
Keep Fingers on the CpG Islands
X Zhang, RM Blumenthal, X Cheng - Epigenomes, 2024 - mdpi.com
17 天前 - … mouse embryos. Notably, the resulting DNA methylation patterns were stable in adult
mice … de novo DNA methylation at previously unmethylated CGIs using ZF fusion proteins. …
mice … de novo DNA methylation at previously unmethylated CGIs using ZF fusion proteins. …
iPS cell generation-associated point mutations include many C> T substitutions via different cytosine modification mechanisms
R Araki, T Suga, Y Hoki, K Imadome… - Nature …, 2024 - nature.com
25 天前 - … and mouse iPSC lines that genomic mutations are de novo events and that, in addition
to unmodified cytosine base prone to deamination, the DNA methylation … reprogramming, …
to unmodified cytosine base prone to deamination, the DNA methylation … reprogramming, …
Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso
H Matsuzaki, M Kimura, M Morihashi… - Epigenetics & Chromatin, 2024 - Springer
31 天前 - … and protects it from genome-wide reprogramming after fertilization. We also identified
a … somatic cells of wild-type mice, we found DNA methylation level of the endogenous H19 …
a … somatic cells of wild-type mice, we found DNA methylation level of the endogenous H19 …
Maternal loss-of-function of Nlrp2 results in failure of epigenetic reprogramming in mouse oocytes
32 天前 - … transcription and DNA methylation in developing oocytes, we observed no
correlation between gene expression differences and gene-body DNA methylation differences in …
correlation between gene expression differences and gene-body DNA methylation differences in …
Preventing CpG island hypermethylation in oocytes safeguards mouse development
YK Kawamura, EA Ozonov, P Papasaikas, T Kondo… - bioRxiv, 2024 - biorxiv.org
36 天前 - … We refer to Ctrl mice as genetically modified mice that we … We refer to wt mice as
genetically non-modified mice that we … of intragenic DNA methylation in mouse gametic DNA …
genetically non-modified mice that we … of intragenic DNA methylation in mouse gametic DNA …
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