Association of mu-opioid receptor expression with lymph node metastasis in esophageal squamous cell carcinoma

YF Zhang, QX Xu, LD Liao, XE Xu, JY Wu… - Diseases of the …, 2015 - academic.oup.com
… MOR1 has been found in several types of cancer cells and reported to be … cell carcinoma
(ESCC) remain unclear. In our study, the expression of MOR1 was confirmed in ESCC cell lines …

[HTML][HTML] The mu-opioid receptor is a molecular marker for poor prognosis in hepatocellular carcinoma and represents a potential therapeutic target

DT Chen, JH Pan, YH Chen, W Xing, Y Yan… - British journal of …, 2019 - Elsevier
… experimental data suggest that opioids might promote tumour … opioid receptors and their
role in directly regulating cellularmu-opioid receptor (MOP) is the main target for most opioids

[HTML][HTML] Increased mu-opioid receptor expression is associated with reduced disease-free and overall survival in laryngeal squamous cell carcinoma

H Zhang, M Sun, D Zhou, A Gorur, Z Sun… - British journal of …, 2020 - Elsevier
… Expression of the mu-opioid receptor (MOR) is associated with … in laryngeal squamous cell
carcinoma (LSCC) is not clear. … oesophageal squamous cell carcinoma or colorectal cancers. …

Mu-opioid receptor activation promotes in vitro and in vivo tumor growth in head and neck squamous cell carcinoma

A Gorur, M Patiño, H Takahashi, G Corrales… - Life Sciences, 2021 - Elsevier
opioids was associated with worse survival in patients undergoing surgery for laryngeal
squamous cell carcinoma (5). The mu-opioid receptor (MOR) is the site of action of prescription …

Targeting the mu-opioid receptor for cancer treatment

H Zhang, D Zhou, J Gu, M Qu, K Guo, W Chen… - Current Oncology …, 2021 - Springer
Opioids are still the most effective and widely used treatments for acute and chronic pain in
cancer patients. This review focuses on the impact of opioids and mu-opioidcell carcinoma

The mu opioid receptor: a new target for cancer therapy?

PA Singleton, J Moss, DD Karp, JT Atkins, F Janku - Cancer, 2015 - Wiley Online Library
… human squamous cell carcinoma of the head and neck, low-dose naltrexone (0.1 mg/kg)
significantly reduced tumor volume by up to 84%. This was accomplished without exogenous …

Novel role of the Mu-opioid receptor in pancreatic cancer: potential link between opioid use and cancer progression

MR Haque, U Barlass, A Armstrong, M Shaikh… - Molecular and Cellular …, 2022 - Springer
… target for most clinically used opioids, including morphine. A … opioid use and pancreatic
cancer (PC) progression. We found increased MOR expression in murine and human PC cell

Low doses of methylnaltrexone inhibits head and neck squamous cell carcinoma growth in vitro and in vivo by acting on the muopioid receptor

A Gorur, M Patiño, T Shi, G Corrales… - Journal of Cellular …, 2021 - Wiley Online Library
… A panel of 70 squamous cell carcinoma cell line was used in this study. Their short tandem
repeat and genomic profiles were previously published, as well as their transcriptome profile (…

The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation

B Mathew, FE Lennon, J Siegler… - Anesthesia & …, 2011 - journals.lww.com
carcinoma, adenocarcinoma, or squamous cell carcinoma lung cancer and adjacent
normal tissue. The microscopic images of each slide were scanned and analyzed using …

Antagonists of the mu-opioid receptor in the cancer patient: fact or fiction?

A Belltall, G Mazzinari, O Diaz-Cambronero… - Current Oncology …, 2022 - Springer
… tumor cell proliferation and angiogenesis; no changes in cell survival were … opioid receptor
blockade with a low dose of NTX on the progression of established squamous cell carcinoma