Mucin degrader Akkermansia muciniphila accelerates intestinal stem cell-mediated epithelial development

S Kim, YC Shin, TY Kim, Y Kim, YS Lee, SH Lee… - Gut …, 2021 - Taylor & Francis
Akkermansia muciniphila is a mucin-degrading bacterium and the sole genus of the phylum…
We confirmed that despite being a mucin-degrading bacterium, A. muciniphila paradoxically …

The Mucin Degrader Akkermansia muciniphila Is an Abundant Resident of the Human Intestinal Tract

M Derrien, MC Collado, K Ben-Amor… - Applied and …, 2008 - Am Soc Microbiol
… A 16S rRNA-targeted probe, MUC-1437, was designed and validated in order to determine
the presence and numbers of cells of Akkermansia muciniphila, a mucin degrader, in the …

The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes

…, M Derrien, SA Malfatti, PSG Chain, T Woyke, A Palva… - PloS one, 2011 - journals.plos.org
… Together, we present the genome sequence of Akkermansia muciniphila, as well as a
number of its features that may be important in its ecology and evolution tuned to its niche, the …

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

M Derrien, P Van Baarlen, G Hooiveld, E Norin… - Frontiers in …, 2011 - frontiersin.org
… a substrate for mucus-degrading bacteria. To study the … Akkermansia muciniphila. This
anaerobic bacterium belonging to the Verrucomicrobia is specialized in the degradation of mucin, …

Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium

M Derrien, EE Vaughan… - … of systematic and …, 2004 - microbiologyresearch.org
… In the present study, mucin-degrading bacteria from human faeces were enriched using
a most probable number (MPN) approach in which the medium contained mucin as the sole …

Characterization of three novel β-galactosidases from Akkermansia muciniphila involved in mucin degradation

K Kosciow, U Deppenmeier - International journal of biological …, 2020 - Elsevier
… This organism is a highly potent degrader of intestinal mucins … composition, exact mucin
degrading mechanisms are still … muciniphila and its host, exact mucin degrading processes …

Disease-associated dysbiosis and potential therapeutic role of Akkermansia muciniphila, a mucus degrading bacteria of gut microbiome

V Aggarwal, S Sunder, SR Verma - Folia Microbiologica, 2022 - Springer
muciniphila lies in its potential to degrade mucin, the significant component in mucus. It
consumes mucin as a carbon and … muciniphila is known to competitively inhibit other mucin-…

Mucin as a Functional Niche Is a More Important Driver of In Vitro Gut Microbiota Composition and Functionality than Akkermansia muciniphila Supplementation

F Van Herreweghen, K De Paepe… - Applied and …, 2021 - Am Soc Microbiol
… and activity to improve health has put Akkermansia muciniphila in the spotlight. As a …
Akkermansia muciniphila was isolated from human feces as a mucin-degrading bacterium …

Mucin degradation niche as a driver of microbiome composition and Akkermansia muciniphila abundance in a dynamic gut model is donor independent

F Van Herreweghen, K De Paepe… - FEMS microbiology …, 2018 - academic.oup.com
Akkermansia muciniphila, an abundant mucin degrading intestinal bacterium, has been
correlated with human health in various studies. The in vitro SHIME model was used to reach a …

Elucidation of Akkermansia muciniphila Probiotic Traits Driven by Mucin Depletion

J Shin, JR Noh, DH Chang, YH Kim, MH Kim… - Frontiers in …, 2019 - frontiersin.org
muciniphila. Transcriptome analysis showed that the genes encoding most mucin-degrading
of genes involved in the mucin-degrading pathway and central carbon metabolism. …