DIABLO: an integrative approach for identifying key molecular drivers from multi-omics assays
… Using simulations and benchmark multi-omics studies, we show that DIABLO identifies
features … In two case studies, DIABLO identified both known and novel multi-omics biomarkers …
features … In two case studies, DIABLO identified both known and novel multi-omics biomarkers …
Multi-omics of single cells: strategies and applications
… can be combined into multi-omics assays that provide … The first generation of single-cell
assays selectively measured a single … We have identified five basic strategies for the multi-omics …
assays selectively measured a single … We have identified five basic strategies for the multi-omics …
[HTML][HTML] Making multi-omics data accessible to researchers
… to concentrate on one type of assay (ie transcriptomics) and … assays from the same set of
samples to create multi-omics … facilities that offer affordable omics assays on a service basis, …
samples to create multi-omics … facilities that offer affordable omics assays on a service basis, …
Methods and applications for single-cell and spatial multi-omics
K Vandereyken, A Sifrim, B Thienpont… - Nature Reviews Genetics, 2023 - nature.com
… For single-cell multi-omics assays, this includes the nature of molecular analytes they analyse
as well as the method used for cell barcoding. For spatial multi-omics assays, this includes …
as well as the method used for cell barcoding. For spatial multi-omics assays, this includes …
Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets
… axes of biological and technical variation when multiple omics assays are applied to the
same samples. MOFA is a broadly applicable approach for multi‐omics data integration. …
same samples. MOFA is a broadly applicable approach for multi‐omics data integration. …
Aging biomarkers: from functional tests to multi‐omics approaches
… and noninvasive physiological tests represent one clear way … Despite the apparent simplicity,
these tests predict the risk of … tests, such as pulmonary function tests, cognitive tests, or …
these tests predict the risk of … tests, such as pulmonary function tests, cognitive tests, or …
Functional Heatmap: an automated and interactive pattern recognition tool to integrate time with multi-omics assays
JR Williams, R Yang, JL Clifford, D Watson… - Bmc Bioinformatics, 2019 - Springer
… that enables pattern recognition in time-series multi-omics assays. It significantly reduces the
manual … changes using multi-tissues/conditions on a time-series fashion from omic assays. …
manual … changes using multi-tissues/conditions on a time-series fashion from omic assays. …
Applied molecular-based quality control of biobanked samples for multi-omics approach
A Michalska-Falkowska, J Niklinski, H Juhl, A Sulewska… - Cancers, 2023 - mdpi.com
… Biospecimen and data distribution for the multi-omics … prior to their application in multi-omics
assays, we developed … sufficient to perform further omics assays, we determined the set …
assays, we developed … sufficient to perform further omics assays, we determined the set …
Canonical correlation analysis for multi-omics: Application to cross-cohort analysis
… of multiple assays. We hypothesized that this method would be helpful for high-dimensional
multi-omics … latent variables from high-dimensional multi-omics data and use them to explain …
multi-omics … latent variables from high-dimensional multi-omics data and use them to explain …
Microtechnologies for single-cell and spatial multi-omics
… By contrast, multi-omics assays (Box 1), which are capable of … Single-cell multi-omics
technologies allow the detailed … Large-scale multi-omics profiling can also be achieved in bulk …
technologies allow the detailed … Large-scale multi-omics profiling can also be achieved in bulk …