A multi-omics integrative network map of maize

L Han, W Zhong, J Qian, M Jin, P Tian, W Zhu… - Nature …, 2023 - nature.com
… In contrast to existing regulatory network maps (the relationships between transcription
factors and downstream target genes) in plants 4,15 , our maize multi-omics network map

The technological landscape and applications of single-cell multi-omics

A Baysoy, Z Bai, R Satija, R Fan - Nature Reviews Molecular Cell …, 2023 - nature.com
… discuss multi-omics limitations. We highlight the impact that single-cell multi-omics technologies
… and cancer genetics, and in mapping of cellular spatial information in fundamental and …

Spatiotemporal multi-omics mapping generates a molecular atlas of the aortic valve and reveals networks driving disease

F Schlotter, A Halu, S Goto, MC Blaser, SC Body… - Circulation, 2018 - Am Heart Assoc
… C, CAVD disease stages: Transcriptomics and proteomics heat map and … map of human
CAVD. More broadly, we present a methodological blueprint that can be applied to multi-omics

Integrated multi-omics maps of lower-grade gliomas

H Binder, M Schmidt, L Hopp, S Davitavyan… - Cancers, 2022 - mdpi.com
Multi-omics high-throughput technologies produce data sets which are not restricted to only
… the combined analysis of multi-omics data based on self-organizing maps machine learning. …

Multi-omics approaches to disease

Y Hasin, M Seldin, A Lusis - Genome biology, 2017 - Springer
… Genomic studies provided a very useful framework for mapping and studying specific …
In the early 2000s, array technologies also made it possible to map loci that control gene …

ChIATAC is an efficient strategy for multi-omics mapping of 3D epigenomes from low-cell inputs

H Chai, H Tjong, P Li, W Liao, P Wang… - Nature …, 2023 - nature.com
… , and FAIRE-seq 17 map regions of open chromatin genome-… could efficiently and
simultaneously map open chromatin loci … for more efficient and informative multi-omics analysis. …

Network biology bridges the gaps between quantitative genetics and multi-omics to map complex diseases

S Wu, D Chen, MP Snyder - Current Opinion in Chemical Biology, 2022 - Elsevier
… Emerging in-depth multi-omics profiling technologies have created exciting opportunities
for … to incorporate quantitative genetics results with multi-omics data by network analysis: (a) …

Multi-omics data integration model based on UMAP embedding and convolutional neural network

B ElKarami, A Alkhateeb, H Qattous… - Cancer …, 2022 - journals.sagepub.com
… can better integrate multi-omics maps into the prediction model than SOM. The proposed
model can also be applied to build a multi-omics prediction model for other types of cancer. …

Multi-omics mapping of human papillomavirus integration sites illuminates novel cervical cancer target genes

M Iden, SW Tsaih, YW Huang, P Liu, M Xiao… - British Journal of …, 2021 - nature.com
… Here, we provide details of a multi-omics approach designed to thoroughly annotate HPV
integration events for the identification and prioritisation of putative novel ICC targets, which …

Multi-omics profiling of mouse gastrulation at single-cell resolution

R Argelaguet, SJ Clark, H Mohammed, LC Stapel… - Nature, 2019 - nature.com
… Here we describe a single-cell multi-omics map of chromatin accessibility, DNA methylation
and RNA expression during the onset of gastrulation in mouse embryos. The initial exit from …