Multi-target approach for natural products in inflammation
A Koeberle, O Werz - Drug discovery today, 2014 - Elsevier
… and safety of multi-target natural products, they are still underrepresented as starting points
for multi-target drug discovery. This article provides an overview about the multi-target drug …
for multi-target drug discovery. This article provides an overview about the multi-target drug …
[HTML][HTML] Multi-target approaches in metabolic syndrome
FF Lillich, JD Imig, E Proschak - Frontiers in pharmacology, 2021 - frontiersin.org
… Multi-target approaches aim at … develop multi-target ligands for MetS. Different combinations
of pharmacological targets in context of in vivo efficacy and future perspective for multi-target …
of pharmacological targets in context of in vivo efficacy and future perspective for multi-target …
[HTML][HTML] Multi-target approach for drug discovery against schizophrenia
M Kondej, P Stępnicki, AA Kaczor - International journal of molecular …, 2018 - mdpi.com
… In this scenario, multi-target drugs are a promising approach … In particular these approaches
concern proteins involved in … to design multi-target drugs and show examples of multi-target …
concern proteins involved in … to design multi-target drugs and show examples of multi-target …
The benefits of the multi-target approach in drug design and discovery
LM Espinoza-Fonseca - Bioorganic & medicinal chemistry, 2006 - Elsevier
… : the multi-target approach represents a new challenge for medicinal chemists, pharmacologists,
toxicologists, and biochemists. With much more work, the multi-target approach could …
toxicologists, and biochemists. With much more work, the multi-target approach could …
Potential impact of the multi-target drug approach in the treatment of some complex diseases
… Different approaches have thus been proposed to come up … The multi-target drugs have
recently attracted much attention … the potential impact of multi-target drug approach on various …
recently attracted much attention … the potential impact of multi-target drug approach on various …
[HTML][HTML] Current pharmacotherapy and multi-target approaches for Alzheimer's disease
SL Cheong, JK Tiew, YH Fong, HW Leong, YM Chan… - Pharmaceuticals, 2022 - mdpi.com
… Thus, multi-target strategies have since been undertaken, which … of the multi-target approaches
and examples of multi-target … As a result, multi-target strategies have increasingly been …
and examples of multi-target … As a result, multi-target strategies have increasingly been …
Epigenetic-based therapy: From single-to multi-target approaches
… The multi-target approach examines the effect of drugs within the context of cellular …
approach, which eliminates all possible interactions of the selected target, a multi-target approach …
approach, which eliminates all possible interactions of the selected target, a multi-target approach …
The efficiency of multi-target drugs: the network approach might help drug design
P Csermely, V Agoston, S Pongor - Trends in pharmacological sciences, 2005 - cell.com
… Development of a multi-target drug is likely to produce a drug that interacts with lower …
other multi-target noncompetitive NMDA receptor antagonists show that low-affinity, multi-target …
other multi-target noncompetitive NMDA receptor antagonists show that low-affinity, multi-target …
A multi-target approach to estimate software vulnerability characteristics and severity scores
… In the present research, the artifact is the multi-target approach that combines text analysis
and multi-target classification techniques and predicts the vulnerability characteristics and …
and multi-target classification techniques and predicts the vulnerability characteristics and …
Search-based testing of procedural programs: Iterative single-target or multi-target approach?
… between the two families of approaches, ie, iterative single-target and multi-target. Indeed,
LIPS was properly customized to share with whole suite approaches the main goals of …
LIPS was properly customized to share with whole suite approaches the main goals of …