[HTML][HTML] A network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of action
X Li, L Wu, W Liu, Y Jin, Q Chen, L Wang, X Fan, Z Li… - PloS one, 2014 - journals.plos.org
… to unravel the complex and holistic mechanisms of TCM in treating … and the underlying
molecular mechanisms of actions of … multi-compound, multi-target and multi-pathway mechanism. …
molecular mechanisms of actions of … multi-compound, multi-target and multi-pathway mechanism. …
[HTML][HTML] Pharmacological actions of multi-target-directed evodiamine
H Yu, H Jin, W Gong, Z Wang, H Liang - Molecules, 2013 - mdpi.com
… that it is good starting point for multi-target drugs. This review is … , with a focus on
pharmacological mechanism. The present … to provide a direction for further multi-target drug …
pharmacological mechanism. The present … to provide a direction for further multi-target drug …
Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles
J Tang, T Aittokallio - Current pharmaceutical design, 2014 - ingentaconnect.com
… targets either by multitarget drugs or targeted drug combinations. Such multi-target treatments
are being considered as a promising strategy to tackle the compensatory mechanisms and …
are being considered as a promising strategy to tackle the compensatory mechanisms and …
[HTML][HTML] Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach
Y Song, H Wang, Y Pan, T Liu - Biomolecules, 2019 - mdpi.com
… To better understand the pharmacological mechanisms of HDW as a therapy for PCa, in this
study, we applied the network pharmacology approach to explore the potential mechanisms …
study, we applied the network pharmacology approach to explore the potential mechanisms …
[HTML][HTML] Network Pharmacology and Bioinformatics Approach Reveals the Multi-Target Pharmacological Mechanism of Fumaria indica in the Treatment of Liver …
… for determining the efficacy of multicomponent, multi-target drug treatment as well as …
pharmacology along with molecular docking was employed to explore the underlying mechanism …
pharmacology along with molecular docking was employed to explore the underlying mechanism …
[HTML][HTML] Integrating Network Pharmacology and Molecular Docking Approaches to Decipher the Multi-Target Pharmacological Mechanism of Abrus precatorius L …
… The small amount of reported data and multiple spectra of pathophysiological mechanisms
… molecular mechanism remains unclarified. In the present study, a network pharmacology …
… molecular mechanism remains unclarified. In the present study, a network pharmacology …
[HTML][HTML] A combined molecular biology and network pharmacology approach to investigate the multi-target mechanisms of Chaihu Shugan San on Alzheimer's …
Q Zeng, L Li, W Siu, Y Jin, M Cao, W Li, J Chen… - Biomedicine & …, 2019 - Elsevier
… elucidate the multi-target mechanisms of CSS on AD using network pharmacology analysis
… The present study systematically revealed the multi-target mechanisms of CSS on AD using …
… The present study systematically revealed the multi-target mechanisms of CSS on AD using …
[HTML][HTML] Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective
A Talevi - Frontiers in pharmacology, 2015 - frontiersin.org
… serendipity or through exploitation of the original action mechanism of a drug for new
indications (on target repositioning). Multi-target agents are natural candidates for more innovative, …
indications (on target repositioning). Multi-target agents are natural candidates for more innovative, …
Multi-target pharmacological mechanisms of Salvia miltiorrhiza against oral submucous fibrosis: A network pharmacology approach
X Cai, H Zhang, T Li - Archives of Oral Biology, 2021 - Elsevier
… , the mechanism underlying its efficacy has not been elucidated. As such, a network
pharmacology-based approach was applied to investigate the potential mechanisms of Salvia …
pharmacology-based approach was applied to investigate the potential mechanisms of Salvia …
Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature
… This study illustrated the mechanisms of pleiotropic activity of green tea polyphenolics towards
cancer, diabetes, neurodegenerative disease, cardiovascular disease, muscular disease, …
cancer, diabetes, neurodegenerative disease, cardiovascular disease, muscular disease, …
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