Toripalimab plus chemotherapy as second-line treatment in previously EGFR-TKI treated patients with EGFR-mutant-advanced NSCLC: a multicenter phase-II trial

T Jiang, P Wang, J Zhang, Y Zhao, J Zhou… - … and Targeted Therapy, 2021 - nature.com
… This study was a multicenter, open-label, phase-II clinical trial evaluating the safety and …
with EGFR-sensitive mutations after failure of EGFR-TKI therapy (NCT03513666). The study was …

SELECT: A multicenter phase II trial of adjuvant erlotinib in resected early-stage EGFR mutation-positive NSCLC.

NA Pennell, JW Neal, JE Chaft, CG Azzoli, PA Janne… - 2014 - ascopubs.org
… Background: EGFR mutant NSCLC is exquisitely sensitive to EGFR tyrosine kinase inhibitors
(… This trial is the first to prospectively test the efficacy of adjuvant erlotinib in EGFR-mutant

Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive non–small cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
… ) in patients with prior systemic treatment for EGFR mutation–positive NSCLC. Based on the
EGFR mutation–positive NSCLC. We thus conducted this multicenter phase 2 clinical trial to …

A multicenter phase II study to evaluate the efficacy and safety of gefitinib as first-line treatment for Korean patients with advanced pulmonary adenocarcinoma …

DW Kim, SH Lee, JS Lee, MA Lee, JH Kang, SY Kim… - Lung cancer, 2011 - Elsevier
… of large-scale screening for EGFR mutations and efficacy of erlotinib in … mutations in this
study was similar to those typically reported with first-line cytotoxic chemotherapy in this setting [2

The SELECT study: A multicenter phase II trial of adjuvant erlotinib in resected epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer …

JW Neal, NA Pennell, R Govindan, M Lanuti… - 2012 - ascopubs.org
… Background: Cancers with activating EGFR mutations are exquisitely sensitive to EGFR
EGFR mutants. This prospective trial investigates the safety and efficacy of adjuvant erlotinib in …

Osimertinib for patients with non–small-cell lung cancer harboring uncommon EGFR mutations: a multicenter, open-label, phase II trial (KCSG-LU15-09)

JH Cho, SH Lim, HJ An, KH Kim, KU Park… - Journal of Clinical …, 2020 - ascopubs.org
… active against most uncommon EGFR mutations, apart from exon … osimertinib for NSCLC
with uncommon EGFR mutations. Here, we … EGFR mutations from a multicenter phase II study. …

… in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 study

T Seto, T Kato, M Nishio, K Goto, S Atagi… - The lancet …, 2014 - thelancet.com
… factor in this trial. Because of this limitation, we undertook this phase 2 trial to examine the
combination of erlotinib and bevacizumab in patients with EGFR mutation-positive NSCLC. …

Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan …

K Tamura, I Okamoto, T Kashii, S Negoro… - British journal of …, 2008 - nature.com
… We performed a multicentre phase II study examining the use of gefitinib for advanced
NSCLC in patients with EGFR mutations, prospectively recruiting patients at the time of genetic …

A novel third-generation EGFR tyrosine kinase inhibitor abivertinib for EGFR T790M-mutant non–small cell lung cancer: a multicenter Phase I/II study

Q Zhou, L Wu, P Hu, T An, J Zhou, L Zhang, XQ Liu… - Clinical Cancer …, 2022 - AACR
… In this study, we report a phase I/II study result to determine the recommended phase II dose
(… Other key inclusion criteria for phase II included an EGFR T790M mutation-positive patient …

[HTML][HTML] A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma

JA Chan, LS Blaszkowsky, PC Enzinger, DP Ryan… - Annals of oncology, 2011 - Elsevier
… antibody to EGFR, in … of EGFR through use of a monoclonal antibody is safe and effective
in patients with esophagogastric cancer, we initiated a multi-institutional phase II study of …