Efficacy and safety of erlotinib in the treatment of metastatic non-small-cell lung cancer

S Ricciardi, S Tomao, F de Marinis - Lung Cancer: Targets and …, 2010 - Taylor & Francis
… The Tarceva or Chemotherapy (TORCH) study Citation49 is a Phase III randomized,
multicenter trial based on a noninferiority survival comparison between an experimental strategy …

Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
… a multicenter (17 centers in China), open-label, phase II, randomized controlled trial of erlotinib
… Patients received erlotinib 150 mg/d (neoadjuvant therapy, 42 days; adjuvant therapy, up …

Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer

EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
… This multicenter, randomized, open-label phase II trial compared the objective response
rate (ORR) as defined by RECIST 1.0 in the erlotinib plus fulvestrant arm versus erlotinib alone …

Phase II clinical trial of chemotherapy-naive patients≥ 70 years of age treated with erlotinib for advanced non–small-cell lung cancer

DM Jackman, BY Yeap, NI Lindeman… - Journal of Clinical …, 2007 - ascopubs.org
… This is a phase II, multicenter, open-label study of … of erlotinib in patients experiencing
treatment failure with one to two prior regimens, 9 we conducted a phase II study of erlotinib in …

A randomized Phase 2 study to compare erlotinib with or without bevacizumab in previously untreated patients with advanced non–small cell lung cancer with EGFR …

Y Lee, HR Kim, MH Hong, KH Lee, KU Park, GK Lee… - Cancer, 2023 - Wiley Online Library
… This study is a multicenter, prospective, open-label, randomized, Phase 2 study that was
conducted at four medical centers in South Korea (ClinicalTrials.gov, no. NCT03126799). …

Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCIC IND-148

AM Oza, EA Eisenhauer, L Elit, JC Cutz… - Journal of Clinical …, 2008 - ascopubs.org
… This was a nonrandomized, nonblinded, multicenter phase II trial to investigate the efficacy
of erlotinib in patients with locally advanced, recurrent and/or metastatic carcinoma of the …

Pemetrexed versus erlotinib in pretreated patients with advanced non–small cell lung cancer: a Hellenic Oncology Research Group (HORG) randomized phase 3 …

A Karampeazis, A Voutsina, J Souglakos… - Cancer, 2013 - Wiley Online Library
… or second‐line treatment were randomized to receive either pemetrexed or erlotinib. In total,
… of patients in the erlotinib arm had squamous cell histology, and treatment was third line in …

Results from the phase III randomized trial of onartuzumab plus erlotinib versus erlotinib in previously treated stage IIIB or IV non–small-cell lung cancer: METLung

DR Spigel, MJ Edelman, K O'Byrne… - Journal of Clinical …, 2017 - ascopubs.org
multicenter, double-blind, placebo-controlled phase III trial evaluating the efficacy and safety
of onartuzumab plus erlotinib … when treated with a combination of onartuzumab and erlotinib

Randomized trial of erlotinib plus whole-brain radiotherapy for NSCLC patients with multiple brain metastases

SM Lee, CR Lewanski, N Counsell… - JNCI: Journal of the …, 2014 - academic.oup.com
… , multicenter, phase II double-blind, placebo controlled trial (NCT00554775). Multicenter
Adverse events were recorded up to 28 days after finishing erlotinib treatment, and graded …

Phase III clinical trial for the combination of erlotinib plus ramucirumab compared with osimertinib in previously untreated advanced or recurrent non–small cell lung …

N Haratake, H Hayashi, M Shimokawa, Y Nakano… - Clinical lung cancer, 2022 - Elsevier
… WJOG14420L), was designed as a multicenter, randomized phase III clinical trial (Figure
1). The primary objective of the study is to evaluate the efficacy of the combination of erlotinib