… multicentre study of people with multiple sclerosis, unaffected siblings, and unrelated healthy
volunteers. We enrolled the study … 177 adults: 79 with multiple sclerosis, 55 siblings, and 43 …

… as an off-label treatment option for multiple sclerosis (MS). … study adds to the published
literature confirming that RTX is effective and relatively safe in the treatment of multiple sclerosis…

… Sequence-related variability of measurements makes the standardization of MT MRI
acquisition essential for the design of multicentre studies. Multiple Sclerosis 2008; 14: 455—464. …

… In a subsequent European multi-centre study (MIMS study) 194 patients with active RR MS
with incomplete recovery or SP MS were randomized to receive Mitoxantrone at a dose of 5 …

Background Previous trials of interferon β in multiple sclerosis (MS) have shown efficacy,
but the degree of clinical benefit remains uncertain, and the optimum dose is not known. We …

… Cognitive decline has been recognised as a frequent symptom in multiple sclerosis (MS).
Cholinesterase inhibitors (ChEIs) are employed for the treatment of Alzheimer’s disease, but …

… Indeed, variability of MR protocols, scanners, use of gadolinium and interpretation of what
constitutes a CV mean that large-scale, multicentre studies are still needed to address the …

… For example, in cases where MRI confirmed the diagnosis of multiple sclerosis, clinicians
were already confident of the diagnosis before imaging (median confidence 86.5%), whereas …

… , and new insights into multiple sclerosis disease activity from studies using high-field and
… In a study comparing patients with multiple sclerosis with those with primary and secondary …

Frontiers | A metformin add-on clinical study in multiple sclerosis to evaluate brain
remyelination and neurodegeneration (MACSiMiSE-BRAIN): study protocol for a multi-center …