… adductomics approach is required that can simultaneously screen for multiple DNA adducts
derived from known and unknown exposures and from biological responses to exposures …

… Some N7-alkylguanines (which are for many alkylating agents the most abundant DNA adduct…
, in which the adduct is detected by multiple reaction monitoring of the fragmentation MH + …

… differed markedly suiting our goal to develop a versatile method for the quantification of
multiple DNA adducts that may be easily extended to the quantification of other adducts in the …

… for the formation of etheno-DNA adducts through reaction of DNA bases with epoxy derivatives
of α,β-… Figure 1 Structures of target oxidative DNA adducts and sites of labeling in internal …

… In this study, multiple DNA adducts were detected in human lymphocytes with the PI nuclease
modification of the 32Ppostlabeling method. For the subjects sampled, the pattern of these …

… total aromatic–DNA adducts and putative BPDE–DNA adducts were found to be higher in
smokers than in non-smokers by 32 P-postlabeling. In other studies on PAH–DNA adducts in …

… While multiple experimental methodologies have been developed for DNA adduct
analysis in … As typical DNA adduct concentrations in biological samples are between 0.01–10 …

… of DNA adducts. In this review, we summarized the development of MS techniques on these
fronts for DNA adduct … multiple DNA adducts derived from different genotoxic agents in …

… The simultaneous measurement of multiple DNA adducts, or DNA adductomics, by different
MS scanning approaches, has recently been reviewed.225, 226 Due to the complexity of the …

… as DNA adducts (3-6) (Figure 1). Depending upon their structure, DNA adducts may (1) block
or significantly slow DNA … His group found that multiple adduct spots are detectable in DNA …