… of cancer, it has been revealed that carcinogenesis is a multistep process involving
alterations of multiple genes, such as point mutation, recombination, amplification, and/or deletion. …

… Multiple genetic and epigenetic alterations in oncogenes, tumour-suppressor genes, cell-cycle
regulators, … instability may be implicated in two distinct major genetic pathways for gastric …

… of multiple genes involved in several molecular pathways in gastric carcinogenesis, … , 15
The present study showed concordant methylation of multiple genes or loci in MSI-positive GCs, …

… of multiple genes and reported that EpsteinBarr virus (EBV)-positive gastric carcinoma …
Therefore, we investigated methylation of multiple genes in primary gastric carcinoma specimens, …

… , and 44.6% had methylation in 2 or more of these genes. Methylation of RB1 was … gene
methylation. This study indicates that aberrant methylation of multiple genes is involved in gastric …

… genes, cell adhesion molecules and genetic instability [1] (Table 1). Interestingly, the scenarios
of multiple gene changes in gastric … different types may have different genetic pathways. …

… gastric carcinoma cell lines, 26 frozen gastric carcinoma tissues and their adjacent nontumor
area for concurrent CpG‐island hypermethylation in 6 tumor‐related genes (… gastric tissues …

… we performed CNA analysis on multiple regions of a single intramucosal gastric carcinoma.
… We examined 25 patients with multiple intramucosal gastric carcinoma diagnosed at Kyoto …

… Gastric carcinoma (GC) is one of the most common malignancies worldwide. To better
understand the genetic basis of this disease, we performed serial analysis of gene expression (…

… or multiple early or advanced carcinomas. Our results suggest that in at least a high proportion
of patients with gastric cancer multiple … conditions leading to similar genetic alterations. …