… it predicts interacting residues that form recognition patches, it gives insights into the origins
of these patches and it enables to contrast the different properties of the interacting residues …

… The presence of two recognition patches at the antibody-combining sites is a consequence
of the clustering procedure, which we ran separately on the heavy and light chains. The …

… here, is the identification of putative interaction sites upon the … protein, known to be involved
in protein-protein interactions, but … any two patches in the set of three was ⩾50% then the two …

… to compare how such interaction patches differ from other sites on the protein surface. To …
recognition site requires largely polar interactions and hence the interface between the two …

… of protein−protein interactions, we can map cellular pathways and their intricate cross-connectivity
(eg, refs 7−11). Since two protein … Identification of protein−protein interactions is at the …

… recognition of protein–protein interaction sites in the case when the structure of an isolated
… literature, we also used two sets of complexes and interaction interfaces developed before by …

… of the two proteins, the interaction of which … protein-protein recognition while large patches
might contain a rather high fraction of atoms that are outside the protein-protein interaction …

… Interestingly, we found a six residue high-propensity binding patch in the ligand, located
correctly (83% accuracy) in one of the two experimental ligand interaction sites: indeed the one …

… Using this patch-based model, we define different interacting … , there are two predicted
targets: residues and patches. Most … Two datasets are used to validate our method and directly …

… For interfaces with multiple recognition patches, one patch is generally larger and has a …
found in single-patch interfaces. The presence of recognition patches at protein interfaces is …