Estimation of multivariate frailty models using penalized partial likelihood

S Ripatti, J Palmgren - Biometrics, 2000 - academic.oup.com
frailtiesmodel based on multiplicative frailties with a multivariate log-normal joint distribution.
We give a justification and an estimation procedure for this generally structured frailty model

A comparison of frailty models for multivariate survival data

A Pickles, R Crouchley - Statistics in Medicine, 1995 - Wiley Online Library
Multivariate survival data allow the hazard function to be estimated with either finite or infinite
mean frailty … assumptions for multivariate survival analysis, describing various models, their …

Bivariate frailty model for the analysis of multivariate survival time

X Xue, R Brookmeyer - Lifetime Data Analysis, 1996 - Springer
… univariate frailty model in analysis of multivariate survival data, a bivariate frailty model is …
The approach involves incorporating into the model two possibly correlated frailties for each …

[PDF][PDF] Frailty models

A Wienke - Rostock, Germany Max Planck institute for …, 2003 - ressources-actuarielles.net
… , a frailty model is a random effect model for time-to-event data, where the random effect (the
frailty) has … Examples of the use of multivariate frailty models are various and emphasize the …

Multivariate frailty models for two types of recurrent events with a dependent terminal event: application to breast cancer data

Y Mazroui, S Mathoulin‐Pélissier… - Biometrical …, 2013 - Wiley Online Library
… We propose a multivariate frailty model that jointly analyzes two types of recurrent events
with a dependent terminal event. Two estimation methods are proposed: a semiparametrical …

A tutorial on frailty models

TA Balan, H Putter - Statistical methods in medical research, 2020 - journals.sagepub.com
… software packages for frailty models and the representation of … the frailty models. Finally, in
section 6, we illustrate the application of frailty models in two common situations, the modeling

A frailty model approach for regression analysis of multivariate current status data

MH Chen, X Tong, J Sun - Statistics in medicine, 2009 - Wiley Online Library
… of the marginal frailty model to multivariate current status … assumed the proportional hazards
frailty model and this may … the model or to compare the appropriateness of different models. …

Model selection for multi‐component frailty models

ID Ha, Y Lee, G MacKenzie - Statistics in medicine, 2007 - Wiley Online Library
… Various frailty models have been developed and are now widely used for analysing
multivariate survival data. It is therefore important to develop an information criterion for …

Maximum likelihood inference for multivariate frailty models using an automated Monte Carlo EM algorithm

S Ripatti, K Larsen, J Palmgren - Lifetime Data Analysis, 2002 - Springer
… This paper describes full likelihood inference for the multivariate frailty model and uses
as an example the multivariate log-normal frailty model. To maximize the likelihood, the EM-…

A dynamic frailty model for multivariate survival data

H Yue, KS Chan - Biometrics, 1997 - JSTOR
… For such data, the identical frailty model may be … identical frailty model by allowing the frailty
to vary stochastically over the indices. We propose a simple updating scheme for the frailties